Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329986 | 0.91 | RAB9A (0.47) | RAB9ANPC1MEN1CYP3A4CYP2C19 | |
| SCHEMBL6858339 | 0.89 | CTSD (0.46) | RAB9ANPC1MEN1CYP3A4CYP2C19 | |
| SCHEMBL4668525 | 0.88 | HTR2A (0.48) | RAB9ANPC1MEN1CYP3A4CYP2C19 | |
| SCHEMBL26365149 | 0.85 | SMN1; SMN2 (0.48) | RAB9ANPC1MEN1CYP3A4CYP2C19 | |
| SCHEMBL7407867 | 0.84 | CTSD (0.57) | RAB9ANPC1MEN1CYP3A4CYP2C19 | |
| SCHEMBL23124356 | 0.84 | HTT (0.48) | NPC1MEN1CYP3A4KMT2ASMN1; SMN2 | |
| SCHEMBL9249682 | 0.83 | CTSD (0.53) | RAB9ANPC1MEN1CYP3A4CYP2C19 | |
| SCHEMBL18089348 | 0.82 | HTT (0.50) | NPC1MEN1CYP3A4KMT2AALDH1A1 | |
| SCHEMBL4185655 | 0.82 | ALDH1A1 (0.66) | MEN1CYP3A4CYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL15953682 | 0.82 | CYP3A4 (0.44) | RAB9ANPC1MEN1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9574189-B2 | Enzymatic encoding methods for efficient synthesis of large libraries | NUEVOLUTION A/S (DK) | 2017-02-21 | — | — | US | disclosed |
| US-20090264300-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | NUEVOLUTION A/S (DK) | 2009-10-22 | — | — | US | disclosed |
| EP-1588173-B1 | AFFINITY FISHING FOR LIGANDS AND PROTEINS RECEPTORS | NOVO NORDISK AS (DK) | 2008-11-26 | — | — | EP | disclosed |
| US-20050148031-A1 | Catalytic efficiency and/or specificity of non-native substrates of enzymes | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-07-07 | — | — | US | disclosed |
| WO-2004068139-A2 | IMPROVEMENT OF CATALYTIC EFFICIENCY AND/OR SPECIFICITY OF NON-NATIVE SUBSTRATES OF ENZYMES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-08-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264300-A1 | ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES | RNGTT, DUT, EMG1 | RAB9A 3185/4885NPC1 4720/4885MEN1 3861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.