Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415175 | 0.99 | CTSD (0.53) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7407867 | 0.96 | CTSD (0.57) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9250162 | 0.90 | RAB9A (0.54) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7410818 | 0.90 | CTSD (0.45) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL7414510 | 0.86 | CTSD (0.49) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6858339 | 0.85 | CTSD (0.46) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL4668525 | 0.84 | HTR2A (0.48) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL6326183 | 0.83 | RAB9A (0.50) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL26365149 | 0.83 | SMN1; SMN2 (0.48) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL15264785 | 0.82 | RAB9A (0.52) | CTSDRAB9ASMN1; SMN2NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446194-A | Pharmacologically active catechol derivatives | ORION-YHTYMA OY (FI) | 1995-08-29 | — | — | US | disclosed |
| US-5283352-A | Transferase inhibitor | ORION-YHTYMA OY (FI) | 1994-02-01 | — | — | US | disclosed |
| US-5112861-A | Inhibitors of catechol-methyl-transferase enzyme, levodopa | ORION-YHTYMA OY (FI) | 1992-05-12 | — | — | US | disclosed |
| US-4963590-A | ENZYME INHIBITOR FOR TREATING PARKINSON'S DISEASE ALONG WITH DOPA;POTENTIATION | ORION-YHTYMA OY (FI) | 1990-10-16 | — | — | US | disclosed |
| CN-87108011-A | New compounds with pharmacological activity, preparation method and related components thereof | ORION YHTYMAE OY (FI) | 1988-06-08 | — | — | CN | disclosed |