Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329986 | 0.90 | RAB9A (0.47) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL4668525 | 0.89 | HTR2A (0.48) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL6326183 | 0.89 | RAB9A (0.50) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL14879925 | 0.86 | TNF (0.50) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL7407867 | 0.86 | CTSD (0.57) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL9249682 | 0.85 | CTSD (0.53) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL6573968 | 0.84 | RAB9A (0.55) | RAB9ASMN1; SMN2NPC1CYP2C19MEN1 | |
| SCHEMBL7415175 | 0.84 | CTSD (0.53) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL9250162 | 0.83 | RAB9A (0.54) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL14829128 | 0.83 | CTSD (0.45) | CTSDRAB9ASMN1; SMN2NPC1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3565484-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2019-11-13 | — | — | EP | claimed |
| WO-2018129369-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2018-07-12 | — | — | WO | claimed |
| US-6787635-B2 | azlactone-functionalized support such as a crosslinked polymer containing an alkenyl azlactone; use making combinatorial libraries | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-07 | — | — | US | claimed |
| EP-4185707-A1 | BASE-MODIFIED NUCLEOTIDES AS SUBSTRATES FOR TDT-BASED ENZYMATIC NUCLEIC ACID | Illumina Singapore Pte Ltd (SG) | 2023-05-31 | — | — | EP | disclosed |
| WO-2023049816-A2 | BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF | FLAGSHIP PIONEERING, INC. (US) | 2023-03-30 | — | — | WO | disclosed |
| EP-3681999-A1 | ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS | The Regents of the University of California (US) | 2020-07-22 | — | — | EP | disclosed |
| EP-3565484-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2019-11-13 | — | — | EP | disclosed |
| WO-2019051428-A1 | ANTIBODY-MEDIATED DELIVERY OF CAS9 TO MAMMALIAN CELLS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-03-14 | — | — | WO | disclosed |
| WO-2018129369-A1 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2018-07-12 | — | — | WO | disclosed |
| WO-2018057941-A1 | MOLECULAR LOGIC GATES FOR CONTROLLED MATERIAL DEGRADATION | UNIVERSITY OF WASHINGTON (US) | 2018-03-29 | — | — | WO | disclosed |
| WO-2016115333-A1 | OPTICAL SELECTION OF CELLS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-07-21 | — | — | WO | disclosed |
| WO-2015168090-A1 | MULTIMODE DEGRADABLE HYDROGELS FOR CONTROLLED RELEASE OF CARGO SUBSTANCES | KIICK KRISTI L (US) | 2015-11-05 | — | — | WO | disclosed |
| WO-2013049521-A2 | LIGHT-ENABLED DRUG DELIVERY | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2013-04-04 | — | — | WO | disclosed |
| US-6515039-B1 | A polyolefin supporting matrix and individual chains of a graft copolymer, which are synthesized by heterogeneous photoinitiated graft copolymerization of acrylate, vinyl and allyl monomers on the surface | POLY-AN GMBH (DE) | 2003-02-04 | — | — | US | disclosed |
| WO-1996000148-A1 | METHODS FOR THE SOLID PHASE SYNTHESIS OF THIAZOLIDINONES, METATHIAZANONES, AND DERIVATIVES THEREOF | AFFYMAX TECHNOLOGIES N.V. (AN) | 1996-01-04 | — | — | WO | disclosed |