Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258551 | 0.73 | RAPGEF3 (0.38) | GAAMAPTLMNAGFERPTK2B | |
| SCHEMBL4668535 | 0.72 | PDE2A (0.33) | SMN1; SMN2ALDH1A1PKML3MBTL1 | |
| SCHEMBL5743661 | 0.70 | GAA (0.37) | GAAMAPTLMNAGFERPTK2B | |
| SCHEMBL3326397 | 0.70 | GAA (0.37) | GAAMAPTLMNAGFERPTK2B | |
| SCHEMBL7744122 | 0.68 | NPSR1 (0.43) | GAAMAPTLMNASMN1; SMN2RAPGEF3 | |
| SCHEMBL7744125 | 0.68 | NPSR1 (0.43) | GAAMAPTLMNASMN1; SMN2RAPGEF3 | |
| SCHEMBL2758643 | 0.68 | RAPGEF3 (0.32) | GAAMAPTLMNAGFERPTK2B | |
| SCHEMBL8529740 | 0.67 | GAA (0.36) | GAASMN1; SMN2RAPGEF3RAPGEF4ALDH1A1 | |
| SCHEMBL10569774 | 0.67 | GAA (0.36) | GAAMAPTSMN1; SMN2RAPGEF4ALDH1A1 | |
| SCHEMBL7736233 | 0.67 | RAPGEF3 (0.38) | MAPTSMN1; SMN2RAPGEF3RAPGEF4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7323574-B2 | Process for the preparation of phenyl pyrazole compounds | BASF AGRO B.V. ARNHEM (CH) | 2008-01-29 | — | — | US | disclosed |
| US-20070021620-A1 | Process for the preparation of phenyl pyrazole compounds | MERIAL LIMITED | 2007-01-25 | — | — | US | disclosed |
| US-7129372-B2 | Process for the preparation of phenyl pyrazole compounds | BASF Agro B.V., Amhem (NL)—Wadenswil Branch (CH) | 2006-10-31 | — | — | US | disclosed |
| EP-1378506-B1 | Process for the preparation of phenyl pyrazole compounds | BASF AGRO B V ARNHEM NL WAEDEN (CH) | 2006-07-26 | — | — | EP | disclosed |
| US-20060052614-A1 | Process for the preparation of phenyl pyrazole compounds | MERIAL LIMITED | 2006-03-09 | — | — | US | disclosed |
| WO-2004005245-A1 | PROCESS FOR THE PREPARATION OF PHENYL PYRAZOLE COMPOUNDS | BASF AGRO B.V. ARNHEM (NL) (CH) | 2004-01-15 | — | — | WO | disclosed |
| EP-1378506-A1 | Process for the preparation of phenyl pyrazole compounds | Bayer CropScience S.A. (FR) | 2004-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021620-A1 | Process for the preparation of phenyl pyrazole compounds | ALG3, KCNH3, KCNA3 | GAA 824/4885MAPT 2332/4885LMNA 2230/4885 |
| US-20060052614-A1 | Process for the preparation of phenyl pyrazole compounds | F5, CYP4F3, ALG3 | GAA 864/4885MAPT 2457/4885LMNA 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.