Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | STS | P08842 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4667754 | 0.84 | STS (0.67) | LMNASTSCYP19A1ALDH1A1VCAM1 | |
| SCHEMBL4668707 | 0.81 | XDH (0.52) | LMNASMN1; SMN2ALDH1A1MEN1MAPK1 | |
| SCHEMBL6806229 | 0.79 | SMN1; SMN2 (0.64) | LMNASMN1; SMN2ALDH1A1MEN1MAPK1 | |
| SCHEMBL8140554 | 0.79 | VCAM1 (0.60) | LMNASMN1; SMN2ALDH1A1MEN1RAB9A | |
| SCHEMBL14596896 | 0.78 | SMN1; SMN2 (0.68) | LMNASMN1; SMN2ALDH1A1MEN1MAPK1 | |
| SCHEMBL6798309 | 0.77 | CYP19A1 (0.53) | STSCYP19A1ALDH1A1HTTRAB9A | |
| SCHEMBL9373575 | 0.77 | VCAM1 (0.54) | LMNASMN1; SMN2ALDH1A1MEN1MAPK1 | |
| SCHEMBL4667310 | 0.74 | VCAM1 (0.54) | LMNASMN1; SMN2CYP19A1ALDH1A1MEN1 | |
| SCHEMBL7023145 | 0.74 | VCAM1 (0.57) | LMNASMN1; SMN2ALDH1A1MEN1RAB9A | |
| SCHEMBL4665389 | 0.72 | STS (0.50) | LMNASMN1; SMN2STSCYP19A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762205-B1 | STEROID SULFATASE INHIBITORS WITHOUT ESTROGENIC SIDE EFFECT ACTION | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 2004-07-13 | — | — | US | disclosed |
| EP-1193250-A1 | PHENYL SULFAMATE DERIVATIVES | Teikoku Hormone Mfg. Co., Ltd. (JP) | 2002-04-03 | — | — | EP | disclosed |