SCHEMBL4669501

SCHEMBL4669501

CN(C)c1ccc(/C=N/N(c2ccccc2)c2ccccc2)c(O)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.72
GAA P10253 4/20 0.72
HTT P42858 2/20 0.72
MAPK1 P28482 1/20 0.72
POLB P06746 2/20 0.60
EIF4H Q15056 1/20 0.60
MEN1 O00255 10/20 0.48
KMT2A Q03164 10/20 0.48
ALDH1A1 P00352 7/20 0.48
KDM4E B2RXH2 4/20 0.48
TDP1 Q9NUW8 2/20 0.47
THRB P10828 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
HPGD P15428 1/20 0.45
ALOX12 P18054 1/20 0.45
CYBB P04839 1/20 0.44
NOX4 Q9NPH5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4669503 1.00 MAPT (0.72) MAPTGAAHTTMAPK1POLB
SCHEMBL4668751 0.86 MAPT (0.74) MAPTGAAHTTMAPK1POLB
SCHEMBL4668750 0.86 MAPT (0.74) MAPTGAAHTTMAPK1POLB
SCHEMBL4668744 0.84 MAPT (1.00) MAPTGAAHTTMAPK1POLB
SCHEMBL4668743 0.84 MAPT (1.00) MAPTGAAHTTMAPK1POLB
SCHEMBL1702564 0.83 MAPT (0.51) MAPTGAAHTTMAPK1POLB
SCHEMBL1702562 0.83 MAPT (0.51) MAPTGAAHTTMAPK1POLB
SCHEMBL1132254 0.83 POLB (0.66) MAPTGAAHTTMAPK1POLB
SCHEMBL1132255 0.83 POLB (0.66) MAPTGAAHTTMAPK1POLB
SCHEMBL22203786 0.79 MAPT (0.56) MAPTGAAHTTMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1443365-B1 Organophotoreceptor with charge transport material having an amino-substituted hydrazone group and an epoxy group SAMSUNG ELECTRONICS CO LTD (KR) 2008-02-20 EP disclosed
US-7183028-B2 Organophotoreceptor with novel charge transport compounds having an epoxy group SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-02-27 US disclosed
US-20040157145-A1 Organophotoreceptor with novel charge transport compounds having an epoxy group S-PRINTING SOLUTION CO., LTD. (KR) 2004-08-12 US disclosed
EP-1443365-A1 Organophotoreceptor with charge transport material having an amino-substituted hydrazone group and an epoxy group Samsung Electronics Co., Ltd. (KR) 2004-08-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040157145-A1 Organophotoreceptor with novel charge transport compounds having an epoxy group SLC43A1, SLC16A3, SLC26A3 MAPT 4115/4885GAA 2662/4885HTT 2984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.