Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP8 | P22894 | 2/20 | 0.32 |
| ▸ | MMP13 | P45452 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872283 | 0.94 | TSHR (0.49) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL632477 | 0.94 | TSHR (0.38) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL819333 | 0.90 | THRB (0.37) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL5872260 | 0.89 | THRB (0.38) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL2523004 | 0.83 | TSHR (0.46) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL31127917 | 0.83 | TSHR (0.46) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL3820632 | 0.83 | THRB (0.36) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL1931731 | 0.83 | THRB (0.36) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL31209956 | 0.83 | THRB (0.36) | TSHRTHRBMMP1MMP2MMP9 | |
| SCHEMBL4234133 | 0.81 | MMP1 (0.39) | TSHRTHRBMMP1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851246-B1 | Optical fiber clad with low refractive index photocured composition | LUCENT TECHNOLOGIES INC (US) | 2008-12-10 | — | — | EP | disclosed |
| US-5822489-A | CLADDING ON OPTICAL FIBER MADE OF A CURED MATERIAL COMPRISING A PERFLUOROPOLYETHER OR PERFLUOROHYDROCARBON BACKBONE END CAPPED WITH (METH)ACRYLATE GROUPS VIA URETHANE GROUPS | LUCENT TECHNOLOGIES, INC. (US) | 1998-10-13 | — | — | US | disclosed |
| EP-0851246-A1 | Optical fiber clad with low refractive index photocured composition | LUCENT TECHNOLOGIES INC. (US) | 1998-07-01 | — | — | EP | disclosed |
| EP-0632059-A2 | Interpenetrating networks from unsaturated monomers and thermosetting resins | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |