SCHEMBL5872260

SCHEMBL5872260

C=C(C)C(=O)OCCN(CC)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
TSHR P16473 3/20 0.37
MMP1 P03956 7/20 0.34
MMP2 P08253 7/20 0.34
MMP9 P14780 7/20 0.34
MMP8 P22894 7/20 0.34
MMP13 P45452 7/20 0.34
CA2 P00918 6/20 0.34
CA1 P00915 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819333 0.99 THRB (0.37) THRBTSHRMMP1MMP2MMP9
SCHEMBL632477 0.90 TSHR (0.38) THRBTSHRMMP1MMP2MMP9
SCHEMBL4669429 0.89 TSHR (0.43) THRBTSHRMMP1MMP2MMP9
SCHEMBL1778769 0.84 THRB (0.36) THRBTSHRMMP1MMP2MMP9
SCHEMBL393824 0.84 THRB (0.36) THRBTSHRMMP1MMP2MMP9
SCHEMBL3820632 0.83 THRB (0.36) THRBTSHRMMP1MMP2MMP9
SCHEMBL1931731 0.83 THRB (0.36) THRBTSHRMMP1MMP2MMP9
SCHEMBL31209956 0.83 THRB (0.36) THRBTSHRMMP1MMP2MMP9
SCHEMBL9872283 0.83 TSHR (0.49) THRBTSHRMMP1MMP2MMP9
SCHEMBL4234133 0.82 MMP1 (0.39) THRBTSHRMMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3575334-B1 MOLDING MATERIAL AND METHOD FOR PRODUCING RESIN MOLDED BODY USING SAME UNIV OSAKA (JP) 2023-05-24 EP claimed
US-11623975-B2 Molding material and method for producing resin molded body using same OSAKA UNIVERSITY (JP) 2023-04-11 US claimed
US-20260128194-A1 ELECTRIC WIRE, METHOD FOR PRODUCING ELECTRIC WIRE, AND MASTERBATCH DAIKIN AMERICA, INC. (US) 2026-05-07 US disclosed
US-12537116-B2 Electric wire, method for producing electric wire, and masterbatch DAIKIN AMERICA, INC. (US) 2026-01-27 US disclosed
US-12151406-B2 Mold release agent DAIKIN INDUSTRIES, LTD. (JP) 2024-11-26 US disclosed
US-12091527-B2 Silsesquioxane OCHANOMIZU UNIVERSITY (JP) 2024-09-17 US disclosed
EP-3575334-B1 MOLDING MATERIAL AND METHOD FOR PRODUCING RESIN MOLDED BODY USING SAME UNIV OSAKA (JP) 2023-05-24 EP disclosed
US-11623975-B2 Molding material and method for producing resin molded body using same OSAKA UNIVERSITY (JP) 2023-04-11 US disclosed
CN-113249971-B Core-shell type short-chain fluorine-containing acrylate fabric water-repellent and oil-repellent finishing agent and preparation method and application thereof 义乌市中力工贸有限公司 2022-06-14 CN disclosed
CN-113249971-A Core-shell type short-chain fluorine-containing acrylate fabric water-repellent and oil-repellent finishing agent and preparation method and application thereof 义乌市中力工贸有限公司 2021-08-13 CN disclosed
US-7098282-B2 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK 2006-08-29 US disclosed
US-20050176907-A1 Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2005-08-11 US disclosed
EP-1455201-A1 Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof Novicky, Nick N. (CA) 2004-09-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260128194-A1 ELECTRIC WIRE, METHOD FOR PRODUCING ELECTRIC WIRE, AND MASTERBATCH PRDM7, EED, PRDM9 THRB 2342/4885TSHR 2799/4885MMP1 3292/4885
US-12537116-B2 Electric wire, method for producing electric wire, and masterbatch EEF1E1, EEF1G, MACF1 THRB 2215/4885TSHR 846/4885MMP1 3050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.