SCHEMBL1702564

SCHEMBL1702564

Cc1cc(N(C)C)ccc1C=NN(c1ccccc1)c1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.51
MAPK1 P28482 4/20 0.51
GAA P10253 2/20 0.51
HTT P42858 1/20 0.51
POLB P06746 1/20 0.50
EIF4H Q15056 1/20 0.50
USP2 O75604 1/20 0.41
MEN1 O00255 7/20 0.40
KMT2A Q03164 7/20 0.40
TDP1 Q9NUW8 5/20 0.39
PSMB5 P28074 2/20 0.39
ALDH1A1 P00352 4/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
MCL1 Q07820 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1702562 1.00 MAPT (0.51) MAPTMAPK1GAAHTTPOLB
SCHEMBL9876003 0.88 MAPT (0.55) MAPTMAPK1GAAHTTPOLB
SCHEMBL12677642 0.84 MAPT (0.51) MAPTMAPK1GAAHTTPOLB
SCHEMBL1702573 0.84 MAPT (0.73) MAPTMAPK1GAAHTTPOLB
SCHEMBL1702571 0.84 MAPT (0.73) MAPTMAPK1GAAHTTPOLB
SCHEMBL4669503 0.83 MAPT (0.72) MAPTMAPK1GAAHTTPOLB
SCHEMBL4669501 0.83 MAPT (0.72) MAPTMAPK1GAAHTTPOLB
SCHEMBL22862037 0.82 ALDH1A1 (0.41) MAPTMAPK1GAAHTTPOLB
SCHEMBL358635 0.81 MAPT (0.55) MAPTMAPK1GAAHTTPOLB
SCHEMBL358634 0.81 MAPT (0.55) MAPTMAPK1GAAHTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6645686-B1 Electrophotographic imaging members XEROX CORPORATION 2003-11-11 US claimed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP claimed
EP-0001599-A1 Electrophotographic recording material and its application in a copying process International Business Machines Corporation (US) 1979-05-02 EP claimed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US claimed
US-20150185629-A1 Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-20150185627-A1 Method of Producing Photoconductors Having Titanyl Phthalocyanine and Bisazo Pigments in Dual Charge Generation Layers LEXMARK INTERNATIONAL, INC. (US) 2015-07-02 US disclosed
US-8178265-B2 Electrophotographic photoreceptor having a spectral marker and electrophotographic printer using the same LEXMARK INTERNATIONAL, INC. (US) 2012-05-15 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-7955769-B2 Control of crazing, cracking or crystallization of a charge transport layer in a photoconductor LEXMARK INTERNATIONAL, INC. (US) 2011-06-07 US disclosed
US-20100167191-A1 Electrophotographic Photoreceptor Having a Spectral Marker and Electrophotographic Printer Using the Same BANK TRUST COMPANY, NATIONAL ASSOCIATION 2010-07-01 US disclosed
US-7648811-B2 Branched polyarylene ethers and processes for the preparation thereof XEROX CORPORATION (US) 2010-01-19 US disclosed
US-20090233196-A1 Photoconductors Containing Copper Phthalocyanine and Titanyl Phthalocyanine in the Charge Generation Layer LEXMARK INTERNATIONAL, INC. 2009-09-17 US disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149914-A1 Overcoated electrophotographic imaging member XEROX CORPORATION (US) 1985-07-31 EP disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
EP-0001599-B1 ELECTROPHOTOGRAPHIC RECORDING MATERIAL AND ITS APPLICATION IN A COPYING PROCESS International Business Machines Corporation (US) 1981-10-21 EP disclosed
EP-0001599-A1 Electrophotographic recording material and its application in a copying process International Business Machines Corporation (US) 1979-05-02 EP disclosed
US-4150987-A ELECTROGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1979-04-24 US disclosed