Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287220 | 0.85 | APP (0.38) | CA1CA2CA9CA5AALDH1A1 | |
| SCHEMBL7499271 | 0.78 | APP (0.42) | CA1CA2CA9ALDH1A1APP | |
| SCHEMBL2433532 | 0.77 | NR1H2 (0.35) | ALDH1A1KIF11 | |
| SCHEMBL3829054 | 0.77 | KIF11 (0.45) | ALDH1A1KIF11SCN2A | |
| SCHEMBL1369135 | 0.77 | KIF11 (0.39) | ALDH1A1KIF11HSD11B1POLBLMNA | |
| SCHEMBL6911307 | 0.76 | AKR1C3 (0.40) | AKR1C3AKR1C2ABCC8KCNJ11CA1 | |
| SCHEMBL6513958 | 0.76 | ACHE (0.35) | ALDH1A1POLBLMNAPTGS1 | |
| SCHEMBL27915252 | 0.74 | AKR1C3 (0.52) | AKR1C3AKR1C2ABCC8KCNJ11ALDH1A1 | |
| SCHEMBL11109664 | 0.74 | MAPT (0.40) | CA1CA2CA9ALDH1A1APP | |
| SCHEMBL3556690 | 0.74 | ALDH1A1 (0.34) | ALDH1A1KIF11HSD11B1MAPK1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1999160-A2 | ACRYLATED HYALURONIC ACID | Novozymes Biopolymer A/S (DK) | 2008-12-10 | — | — | EP | disclosed |
| WO-2007106738-A2 | ACRYLATED HYALURONIC ACID | NOVOZYMES BIOPOLYMER A/S (DK) | 2007-09-20 | — | — | WO | disclosed |
| EP-0342152-A2 | Mass-dyed highly molecular organic materials containing metal complexes; metal complexes and process for their preparation | CIBA-GEIGY AG (CH) | 1989-11-15 | — | — | EP | disclosed |
| EP-0036387-B1 | PROCESS FOR THE PREPARATION OF HYDRAZONO-ISOINDOLINES | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0036388-B1 | ISOINDOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1984-02-15 | — | — | EP | disclosed |
| US-4414395-A | REACTING AN IMINOISOINDOLE WITH HYDRAZINE | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| US-4349671-A | Process for the production of metal complexes of isoindoline azines | CIBA-GEIGY CORPORATION (US) | 1982-09-14 | — | — | US | disclosed |
| EP-0036835-A1 | Process for the preparation of metal complexes of isoindoline azines | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036834-A1 | Process for the preparation of metal complexes of isoindoline azines | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036387-A2 | Process for the preparation of hydrazono-isoindolines | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |
| EP-0036388-A2 | Isoindoline derivatives, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |