SCHEMBL4670083

SCHEMBL4670083

O=C(/C=C/c1ccc(O)cc1)Nc1ccc(O)cc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TRPM2 O94759 3/20 0.62
MMP1 P03956 9/20 0.60
MMP2 P08253 9/20 0.60
MMP9 P14780 9/20 0.60
LTB4R Q15722 1/20 0.59
TRPA1 O75762 5/20 0.58
TRPM8 Q7Z2W7 2/20 0.58
DEGS1 O15121 1/20 0.55
MAPT P10636 2/20 0.54
MEN1 O00255 1/20 0.54
NPC1 O15118 1/20 0.54
RAB9A P51151 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
PELI1 Q96FA3 1/20 0.53
CHRNA7 P36544 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5351229 1.00 TRPM2 (0.62) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL29913807 1.00 TRPM2 (0.62) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL6013326 0.93 TRPM2 (0.64) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL4670106 0.93 TRPM2 (0.64) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL18230842 0.92 TRPM2 (0.64) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL25144814 0.90 TRPM2 (0.52) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL9973825 0.90 TRPM2 (0.62) TRPM2MMP1MMP2MMP9LTB4R
SCHEMBL4199528 0.89 MMP1 (0.64) TRPM2MMP1MMP2MMP9TRPA1
SCHEMBL30041332 0.89 MMP1 (0.64) TRPM2MMP1MMP2MMP9TRPA1
SCHEMBL4199523 0.89 MMP1 (0.64) TRPM2MMP1MMP2MMP9TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564551-B2 Composition or oat extract comprising avenanthramide and β-glucan SYMRISE AG (DE) 2026-03-03 US claimed
US-20250212873-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-07-03 US claimed
US-20250051551-A1 IMPROVED POLYMER COMPOSITES WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2025-02-13 US claimed
EP-4487838-A2 AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE Symrise AG (DE) 2025-01-08 EP claimed
EP-4482306-A1 VOLATILE HDAC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-01-01 EP claimed
EP-4114354-B1 AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE SYMRISE AG (DE) 2024-12-11 EP claimed
CN-117814312-A Milk beverage capable of loading different types of polyphenols and preparation method thereof 江苏大学 2024-04-05 CN claimed
CN-117257663-A Avena sativa alkaloid A, B, C composition and application thereof in preparing cosmetic skin soothing agent 福州美乐莲生物科技有限公司 2023-12-22 CN claimed
CN-117099955-A Different pKs can be loaded a Aqueous casein solution of polyphenol and preparation method thereof 江苏大学 2023-11-24 CN claimed
WO-2023192424-A1 VOLATILE HD AC INHIBITORS FOR THERAPEUTIC AND PLANT APPLICATIONS CROSS-REFERENCE TO RELATED APPLICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-10-05 WO claimed
EP-4125984-A1 A CONSUMABLE PRODUCT COMPRISING MALTED CEREALS FOR PROMOTING RECOVERY AT PHYSICAL ACTIVITY Lantmännen Functional Foods AB (SE) 2023-02-08 EP claimed
CN-115605214-A Consumable product comprising malted cereals for promoting recovery of physical activity 兰特门内保健食品公司(SE) 2023-01-13 CN claimed
EP-4114349-A1 COMPOSITION OR OAT EXTRACT COMPRISING AVENANTHRAMIDE AND BETA-GLUCAN Symrise AG (DE) 2023-01-11 EP claimed
EP-4114354-A1 AVENANTHRAMIDE COMPOSITIONS WITH IMPROVED SOLUBILITY COMPRISING 4-HYDROXYPHENONE Symrise AG (DE) 2023-01-11 EP claimed
CN-115554370-A Composition for improving autoimmune thyroiditis and application thereof 陕西中鸿科瑞再生医学研究院有限公司 2023-01-03 CN claimed
CN-115243669-A Avenanthramide compositions with enhanced solubility comprising 4-hydroxybenzophenones 西姆莱斯股份公司 2022-10-25 CN claimed
CN-115243670-A Cosmetic or pharmaceutical use of avenanthramide L 西姆莱斯股份公司 2022-10-25 CN claimed
CN-115209864-A Compositions comprising avenanthramides or analogs thereof having improved stability 西姆莱斯股份公司 2022-10-18 CN claimed
EP-3113754-B1 OXIDATIVE HAIR DYEING COMPOSITION KAO GERMANY GMBH (DE) 2022-07-27 EP claimed
WO-2022128052-A1 MEDICAMENT FOR FIGHTING INFLAMMATORY CONDITIONS OF HUMAN SKIN SYMRISE AG (DE) 2022-06-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564551-B2 Composition or oat extract comprising avenanthramide and β-glucan CUTA, HLA-A, OAT TRPM2 962/4885MMP1 2429/4885MMP2 3268/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.