SCHEMBL467050

SCHEMBL467050

CC1=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc2C1[Zr]C1C(C)=Cc2c(-c3ccc(C(C)(C)C)cc3)cccc21.C[Si](Cl)(Cl)C1CCCCC1

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
XBP1 P17861 1/20 0.31
ALOX12 P18054 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
S1PR1 P21453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21403458 0.88 S1PR1 (0.36) ALDH1A1LMNASMN1; SMN2S1PR1
SCHEMBL4873780 0.81 LMNA (0.33) ALDH1A1LMNAHPGDXBP1ALOX12
SCHEMBL5608036 0.78 ALDH1A1 (0.34) ALDH1A1LMNAHPGDXBP1ALOX12
SCHEMBL14905713 0.76 NPC1 (0.33) ALDH1A1HPGDSMN1; SMN2
Hydrochloric Acid SCHEMBL1915069 0.76
SCHEMBL2388282 0.75 NPC1 (0.35) LMNASMN1; SMN2S1PR1
SCHEMBL31253543 0.75 RXRB (0.35)
Ethylene Glycol SCHEMBL7106493 0.74 GABRA1 (0.33) ALDH1A1
Hydrochloric Acid SCHEMBL6891459 0.73 BRD4 (0.32) ALDH1A1LMNAHPGDXBP1ALOX12
SCHEMBL1455223 0.72 NPC1 (0.36) ALDH1A1LMNASMN1; SMN2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2746336-B1 Polypropylene blend for pressure pipes BOREALIS AG (AT) 2017-04-12 EP claimed
EP-2562215-B1 POLYPROPYLENE BLEND FOR PIPES BOREALIS AG (AT) 2016-03-30 EP claimed
WO-2014095946-A1 POLYPROPYLENE BLEND FOR PRESSURE PIPES BOREALIS AG (AT) 2014-06-26 WO claimed
WO-2013029699-A1 POLYPROPYLENE BLEND FOR PIPES BOREALIS AG (AT) 2013-03-07 WO claimed
EP-2562215-A1 Polypropylene blend for pipes Borealis AG (AT) 2013-02-27 EP claimed
US-20240002555-A1 IN-SITU REACTOR BLEND OF ZIEGLER-NATTA CATALYSED, NUCLEATED POLYPROPYLENE AND A METALLOCENE CATALYSED POLYPROPYLENE BOREALIS AG (AT) 2024-01-04 US disclosed
EP-4247864-A1 IN-SITU REACTOR BLEND OF ZIEGLER-NATTA CATALYSED, NUCLEATED POLYPROPYLENE AND A METALLOCENE CATALYSED POLYPROPYLENE Borealis AG (AT) 2023-09-27 EP disclosed
WO-2022106710-A1 IN-SITU REACTOR BLEND OF ZIEGLER-NATTA CATALYSED, NUCLEATED POLYPROPYLENE AND A METALLOCENE CATALYSED POLYPROPYLENE BOREALIS AG (AT) 2022-05-27 WO disclosed
EP-2487203-B2 Sealing propylene copolymer BOREALIS AG (AT) 2020-11-25 EP disclosed
EP-2978782-B2 PROPYLENE COPOLYMER WITH HIGH IMPACT PROPERTIES BOREALIS AG (AT) 2020-11-18 EP disclosed
US-10640685-B2 Multi-layer blown film BOREALIS AG (AT) 2020-05-05 US disclosed
US-10414135-B2 Multi-layer cast film BOREALIS AG (AT) 2019-09-17 US disclosed
WO-2011131639-A1 PROPYLENE/1-HEXENE COPOLYMER COMPOSITION WITH LOW SEALING TEMPERATURE BOREALIS AG (AT) 2011-10-27 WO disclosed
US-8040790-B2 Low complexity bandwidth efficient carrier frequency offset estimation technique for OFDMA uplink transmissions INDIAN INSTITUTE OF TECHNOLOGY (IN) 2011-10-18 US disclosed
WO-2011080152-A1 NEW WAY TO PRODUCE POLYPROPYLENE GRADE IN A SEQUENTIAL PROCESS BOREALIS AG (AT) 2011-07-07 WO disclosed
WO-2011080153-A1 BOPP-FILM BOREALIS AG (AT) 2011-07-07 WO disclosed
WO-2011080151-A1 BOPP WITH HOMOGENEOUS FILM MORPHOLOGY BOREALIS AG (AT) 2011-07-07 WO disclosed
EP-2341086-A1 Bopp-film Borealis AG (AT) 2011-07-06 EP disclosed
EP-2341087-A1 New way to produce polypropylene grade in a sequential process Borealis AG (AT) 2011-07-06 EP disclosed
EP-2341088-A1 BOPP with homogeneous film morphology Borealis AG (AT) 2011-07-06 EP disclosed