Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | PTAFR | P25105 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873780 | 0.89 | LMNA (0.33) | ALDH1A1LMNAHPGDXBP1ALOX12 | |
| SCHEMBL1455223 | 0.82 | NPC1 (0.36) | ALDH1A1LMNASMN1; SMN2BRD4CREBBP | |
| SCHEMBL2388282 | 0.80 | NPC1 (0.35) | LMNASMN1; SMN2BRD4CREBBPPTAFR | |
| SCHEMBL27199665 | 0.79 | BRD4 (0.31) | ALDH1A1LMNAHPGDXBP1ALOX12 | |
| SCHEMBL5548512 | 0.79 | BRD4 (0.32) | ALDH1A1LMNAHPGDSMN1; SMN2BRD4 | |
| Hydrochloric Acid SCHEMBL27199711 | 0.79 | BRD4 (0.30) | BRD4CREBBP | |
| SCHEMBL16393539 | 0.78 | PDK2 (0.31) | — | |
| SCHEMBL467050 | 0.78 | ALDH1A1 (0.31) | ALDH1A1LMNAHPGDXBP1ALOX12 | |
| SCHEMBL27199727 | 0.78 | — | — | |
| SCHEMBL3402757 | 0.77 | NR1H4 (0.31) | ALDH1A1LMNAHPGDSMN1; SMN2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915824-A1 | METALLOCENE LIGANDS, METALLOCENE COMPOUNDS AND METALLOCENE CATALYSTS, THEIR SYNTHESIS AND THEIR USE FOR THE POLYMERIZATION OF OLEFINS | Lummus Novolen Technology Gmbh (DE) | 2015-09-09 | — | — | EP | disclosed |
| US-7285608-B2 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | NOVOLEN TECHNOLOGY HOLDINGS C.V. (NL) | 2007-10-23 | — | — | US | disclosed |
| US-20050239979-A1 | Metallocene ligands, metallocene compounds and metallocene catalysts, their synthesis and their use for the polymerization of olefins | LUMMUS NOVOLEN TECHNOLOGY GMBH (DE) | 2005-10-27 | — | — | US | disclosed |