Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | TRHR | P34981 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136194 | 0.71 | SIGMAR1 (0.44) | SIGMAR1PRKAA2 | |
| SCHEMBL4670787 | 0.71 | TRHR (0.43) | SIGMAR1TRHRDRD2DRD4DRD3 | |
| SCHEMBL6164881 | 0.68 | LTA4H (0.49) | SIGMAR1DRD2DPP7KCNH2DRD4 | |
| SCHEMBL5230894 | 0.66 | SIGMAR1 (0.74) | SIGMAR1DRD2DPP7KCNH2DRD4 | |
| SCHEMBL7399708 | 0.65 | KDM4C (0.51) | POLBRBP4 | |
| SCHEMBL20925176 | 0.65 | KDM4C (0.48) | POLBRBP4 | |
| SCHEMBL17152266 | 0.65 | SIGMAR1 (0.56) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL5717571 | 0.65 | CPB2 (0.47) | TRHRPOLBRBP4 | |
| Hydrochloric Acid SCHEMBL8762068 | 0.64 | KDM4C (0.50) | RBP4 | |
| SCHEMBL2687705 | 0.64 | EPHX2 (0.62) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903052-A2 | APJ receptor ligands and uses thereof | Faust Pharmaceuticals SA (FR) | 2008-03-26 | — | — | EP | disclosed |