Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TERT | O14746 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | BLM | P54132 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29562542 | 0.79 | ACHE (0.59) | MAPTNPSR1NPC1RAB9AHTT | |
| SCHEMBL29240 | 0.79 | ACHE (0.59) | MAPTNPSR1NPC1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL668151 | 0.77 | ACHE (0.57) | MAPTNPSR1NPC1RAB9AHTT | |
| SCHEMBL17187158 | 0.73 | HPGD (0.41) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL29684245 | 0.73 | HPGD (0.41) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL6646299 | 0.72 | PADI4 (0.38) | MAPTNPSR1NPC1RAB9AHTT | |
| Nitric Acid SCHEMBL29563050 | 0.72 | ACHE (0.55) | MAPTNPSR1NPC1RAB9AHTT | |
| SCHEMBL5455552 | 0.71 | ALDH1A1 (0.40) | MAPTLMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL10748957 | 0.70 | MEN1 (0.33) | MAPTNPSR1NPC1RAB9AHTT | |
| SCHEMBL3425653 | 0.69 | TERT (0.38) | MAPTNPSR1NPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766825-B1 | PREPARATION OF DERIVATIZED 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND SIGNAL SOLUTIONS | KATSILOMETES GEORGE W (US) | 2008-05-28 | — | — | EP | disclosed |
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |
| US-20020034828-A1 | NOVEL 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND THEIR PREPARATION | PIERCE CHEMICAL COMPANY | 2002-03-21 | — | — | US | disclosed |
| EP-1026156-A2 | Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation | PIERCE CHEMICAL COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |
| US-5866335-A | Preparation of derivatized 10,10'-substituted-9,9'-biacridine luminescent molecules and signal solutions | Katsilometes, George W. (US) | 1999-02-02 | — | — | US | disclosed |