SCHEMBL467130

SCHEMBL467130

C=CCc1cc(Cc2cc(CC=C)c(N)c(CC=C)c2)cc(CC=C)c1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 2/20 0.39
GABRA1 P14867 6/20 0.36
GABRB2 P47870 6/20 0.36
MAPT P10636 3/20 0.33
XDH P47989 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 2/20 0.33
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
KMT2A Q03164 2/20 0.33
POLB P06746 2/20 0.33
ALOX5 P09917 1/20 0.33
GABRB1 P18505 1/20 0.33
RXRA P19793 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
GABRA2 P47869 1/20 0.33
ACE2 Q9BYF1 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL466874 0.90 DHFR (0.40) DHFRGABRA1GABRB2MAPTXDH
SCHEMBL11129754 0.89 CYP3A4 (0.50) DHFRGABRA1GABRB2MAPTXDH
SCHEMBL2162708 0.88 XDH (0.39) GABRA1GABRB2MAPTXDHCYP1A2
SCHEMBL467179 0.87 GABRA1 (0.35) DHFRGABRA1GABRB2MAPTXDH
SCHEMBL9288771 0.86 CYP3A4 (0.38) DHFRGABRA1GABRB2CYP3A4ALDH1A1
SCHEMBL9281677 0.86 SHBG (0.39) DHFRGABRA1GABRB2CYP1A2CYP3A4
SCHEMBL1865361 0.81 GABRA1 (0.48) GABRA1GABRB2MAPTXDHCYP1A2
Methane SCHEMBL28151881 0.79 GABRA1 (0.47) GABRA1GABRB2MAPTCYP1A2CYP3A4
SCHEMBL9399710 0.79 GABRA1 (0.38) GABRA1GABRB2MAPTXDHCYP1A2
SCHEMBL9489328 0.77 DHFR (0.48) DHFRGABRA1GABRB2MAPTXDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3046944-B1 METHOD FOR THE PREPARATION OF ORGANIC AEROGELS BASED ON ISOCYANATE BASF SE (DE) 2021-08-11 EP claimed
EP-3169724-B1 PROCESS FOR PRODUCING POROUS MATERIALS BASF SE (DE) 2021-05-26 EP claimed
US-10907024-B2 Process for producing porous materials BASF SE (DE) 2021-02-02 US claimed
EP-2900715-B1 PROCESS FOR THE PREPARATION OF POROUS MATERIALS ON THE BASIS OF POLYURIC MATERIAL BASF SE (DE) 2020-11-25 EP claimed
CN-106795315-B Method for producing porous material 巴斯夫欧洲公司 2020-08-14 CN claimed
US-10717841-B2 Process for producing porous materials BASF SE (DE) 2020-07-21 US claimed
EP-3122809-B1 PROCESS FOR PRODUCING POROUS MATERIALS BASF SE (DE) 2020-06-03 EP claimed
US-10240020-B2 Process for producing porous materials BASF SE (DE) 2019-03-26 US claimed
US-20190023864-A1 PROCESS FOR PRODUCING POROUS MATERIALS BASF SE (DE) 2019-01-24 US claimed
EP-3405508-A1 PROCESS FOR PRODUCING POROUS MATERIALS BASF SE (DE) 2018-11-28 EP claimed
EP-0438695-B1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-benzylurea groups, such elastomers and N-benzyl-polyoxyalkylene-polyamines suitable therefor BASF AG (DE) 1995-09-20 EP claimed
US-5364852-A Molding materials BASF AKTIENGESELLSCHAFT (DE) 1994-11-15 US claimed
EP-0438696-B1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-substituted urea- and amide groups, such elastomers and polyoxyalkylene-polyamine mixtures, containing polyazomethines, suitable therefor BASF AG (DE) 1994-11-02 EP claimed
EP-0573873-A2 Process for the preparation of urethane or urea groups-containing compact or cellular elastomers or mouldings thereof BASF Aktiengesellschaft (DE) 1993-12-15 EP claimed
EP-0284912-B1 Elastomers containing polyamide and polyurea groups and procedure for the preparation of elastic, compact or cellular mouldings thereof BASF AG (DE) 1993-11-24 EP claimed
US-5122547-A PRODUCTION OF ELASTIC, COMPACT OR CELLULAR MOLDINGS BASED ON ELASTOMERS CONTAINING N-BENZYLUREA GROUPS IN BOUND FORM, ELASTOMERS OF THIS TYPE, AND N-BENZYLPOLYOXYALKYLENE-POLYAMINES WHICH ARE SUITABLE FOR THIS PURPOSE BASF AKTIENGESELLSCHAFT (DE) 1992-06-16 US claimed
US-5084487-A Polyetherpolyimine copolymers for reaction injection molding BASF AKTIENGESELLSCHAFT (DE) 1992-01-28 US claimed
EP-0438696-A1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-substituted urea- and amide groups, such elastomers and polyoxyalkylene-polyamine mixtures, containing polyazomethines, suitable therefor BASF Aktiengesellschaft (DE) 1991-07-31 EP claimed
EP-0438695-A1 Process for the preparation of elastic compact or cellular moulded articles on the basis of elastomers containing N-benzylurea groups, such elastomers and N-benzyl-polyoxyalkylene-polyamines suitable therefor BASF Aktiengesellschaft (DE) 1991-07-31 EP claimed
US-4789691-A REACTING POLYISOCYANATE, POLYAZOMETHINE, AND AROMATIC POLYAMINES BASF AKTIENGESELLSCHAFT (DE) 1988-12-06 US claimed