Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.30 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1865361 | 0.83 | GABRA1 (0.48) | GABRA1GABRB2POLBCYP3A4MAPT | |
| SCHEMBL2162708 | 0.81 | XDH (0.39) | GABRA1GABRB2POLBCYP3A4MAPT | |
| SCHEMBL9399475 | 0.79 | GABRA1 (0.36) | GABRA1GABRB2POLB | |
| SCHEMBL20681220 | 0.79 | GABRA1 (0.36) | GABRA1GABRB2POLBCYP3A4ALOX5 | |
| SCHEMBL10410485 | 0.79 | GABRA1 (0.36) | GABRA1GABRB2POLBMAPTCYP1A2 | |
| SCHEMBL467130 | 0.79 | DHFR (0.39) | GABRA1GABRB2POLBCYP3A4MAPT | |
| SCHEMBL671144 | 0.79 | PTGDR (0.40) | GABRA1GABRB2POLBCYP3A4MAPT | |
| SCHEMBL9721939 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2POLBMAPTXDH | |
| Bromide SCHEMBL10410488 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2POLBMAPTMEN1 | |
| SCHEMBL28789107 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2POLBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321067-A | Oxidation, heat resistance | CIBA-GEIGY CORPORATION (US) | 1994-06-14 | — | — | US | disclosed |
| US-5145970-A | Oil additives | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |