Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | XPA | P23025 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.44 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46709 | 0.85 | XPA (0.51) | ALDH1A1KDM4EXPAKMT2AMEN1 | |
| SCHEMBL6721173 | 0.73 | KDM4E (1.00) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL19021491 | 0.72 | ALDH1A1 (0.52) | ALDH1A1KDM4EXPAKMT2AMEN1 | |
| SCHEMBL2556095 | 0.70 | LDHA (0.72) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL46199 | 0.70 | XPA (0.48) | ALDH1A1KDM4EXPAKMT2AMEN1 | |
| SCHEMBL6393879 | 0.70 | TDP1 (0.74) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL5146587 | 0.70 | TDP1 (0.74) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL46215 | 0.69 | ENPP2 (0.75) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL6721163 | 0.69 | ALDH1A1 (0.75) | ALDH1A1KDM4EKMT2AMEN1NPC1 | |
| SCHEMBL17789559 | 0.68 | ALDH1A1 (0.53) | ALDH1A1KDM4EXPAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005800-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRIN CD11B/CD18 | ADHAERE PHARAMACEUTICALS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |