SCHEMBL4672249

SCHEMBL4672249

CCCOC(=O)C(C)(C)[S]

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.39
ALDH1A1 P00352 5/20 0.38
LMNA P02545 2/20 0.36
CHRM1 P11229 2/20 0.35
ESR1 P03372 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A2 P23975 1/20 0.35
KDR P35968 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 1/20 0.33
HSD17B10 Q99714 1/20 0.33
GRM1 Q13255 1/20 0.33
ATM Q13315 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4677246 0.86 ALDH1A1 (0.52) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL4676462 0.85 NAAA (0.50) HCAR2ALDH1A1LMNATSHRATM
SCHEMBL4679750 0.83 NAAA (0.53) HCAR2ALDH1A1LMNATSHR
SCHEMBL21032274 0.80 PDK1 (0.36) HCAR2ALDH1A1LMNACHRM1ESR1
SCHEMBL4672701 0.80
SCHEMBL6062638 0.80 HCAR2 (0.41) HCAR2ALDH1A1LMNACHRM1ESR1
SCHEMBL204763 0.80 POLB (0.44) HCAR2ALDH1A1LMNACHRM1ESR1
SCHEMBL4672467 0.78 HCAR2 (0.40) HCAR2ALDH1A1LMNACHRM1ESR1
Hydrochloric Acid SCHEMBL29154726 0.78 POLB (0.43) HCAR2ALDH1A1LMNACHRM1ESR1
SCHEMBL4672465 0.78 HCAR2 (0.40) HCAR2ALDH1A1LMNACHRM1ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed