SCHEMBL4672255

SCHEMBL4672255

CCCOC(=O)C(C)(C)S

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 1/20 0.39
ALDH1A1 P00352 3/20 0.38
LMNA P02545 2/20 0.36
GRM1 Q13255 1/20 0.36
ESR1 P03372 1/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35
SLC6A2 P23975 1/20 0.35
KDR P35968 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
PPM1B O75688 1/20 0.34
PTPN1 P18031 1/20 0.34
PPP1CC P36873 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
RAB9A P51151 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1171758 0.87 PRKCA (0.34) ALDH1A1CHRM1TSHR
SCHEMBL4677248 0.86 ALDH1A1 (0.52) HCAR2ALDH1A1LMNAESR1TSHR
SCHEMBL4676466 0.85 NAAA (0.50) HCAR2ALDH1A1LMNATSHRCA1
SCHEMBL4463477 0.83 NAAA (0.37) ALDH1A1TSHRCA1CA2
SCHEMBL5610701 0.83 HCAR2 (0.45) HCAR2ALDH1A1LMNAGRM1ESR1
SCHEMBL4679753 0.83 NAAA (0.53) HCAR2ALDH1A1LMNATSHR
SCHEMBL28443270 0.83 NAAA (0.53) HCAR2ALDH1A1LMNATSHR
SCHEMBL1271415 0.81 TSHR (0.38) ALDH1A1TSHR
SCHEMBL4462237 0.81 NAAA (0.40) HCAR2ALDH1A1TSHRCA1CA2
SCHEMBL1171012 0.81 ALDH1A1 (0.38) ALDH1A1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994034-A Aryl uracil compound, preparation method thereof and pesticide composition 深圳大学 2024-11-22 CN disclosed
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
EP-1101761-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL CO (JP) 2005-08-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
US-6339155-B1 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-01-15 US disclosed
EP-1101761-A2 Process for producing 3-phenyluracil compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-23 EP disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed