SCHEMBL4674071

SCHEMBL4674071

Cc1cccc(C)c1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPL P06858 12/20 0.44
LIPG Q9Y5X9 12/20 0.44
IRAK4 Q9NWZ3 1/20 0.36
P2RX7 Q99572 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
CD44 P16070 1/20 0.34
TRPA1 O75762 1/20 0.34
ATM Q13315 1/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA7 P43166 1/20 0.33
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29225823 0.89 LIPG (0.37) LPLLIPGIRAK4CD44CA1
SCHEMBL29897342 0.86 LPL (0.41) LPLLIPGIRAK4P2RX7
SCHEMBL20722870 0.86 LPL (0.38) LPLLIPGIRAK4P2RX7
SCHEMBL29897387 0.86 LPL (0.38) LPLLIPGIRAK4P2RX7
SCHEMBL5840223 0.86 CD44 (0.47) LPLLIPGIRAK4P2RX7CD44
SCHEMBL23301057 0.86 LPL (0.41) LPLLIPGIRAK4P2RX7
SCHEMBL18569315 0.86 LPL (0.38) LPLLIPGIRAK4P2RX7
SCHEMBL31185820 0.84 LPL (0.38) LPLLIPGIRAK4P2RX7CA1
SCHEMBL26647695 0.83 CSF1R (0.38) LPLLIPGCYP1A2CA1CA2
SCHEMBL12665647 0.82 ALDH1A1 (0.46) LPLLIPGIRAK4CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059996-A Organic metal compound and organic electroluminescent device comprising same 吉林奥来德光电材料股份有限公司 2026-05-19 CN disclosed
CN-122036809-A Organic metal compound and organic electroluminescent device comprising same 吉林奥来德光电材料股份有限公司 2026-05-15 CN disclosed
CN-118845703-A High-permeability polymer nanocapsule, and preparation method and application thereof 浙江大学 2024-10-29 CN disclosed
US-20230279025-A1 KRAS G12D INHIBITORS ARRAY BIOPHARMA INC. 2023-09-07 US disclosed
CN-116354993-A Reactive Oxygen Species (ROS) responsive cations and their use in siRNA delivery 中国科学院合肥物质科学研究院 2023-06-30 CN disclosed
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose ABBVIE INC. (US) 2022-04-26 US disclosed
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose ABBVIE INC. (US) 2022-04-26 US disclosed
US-20210017100-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE AbbVie Deutschland GmbH & Co. KG (DE) 2021-01-21 US disclosed
US-20210017100-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE AbbVie Deutschland GmbH & Co. KG (DE) 2021-01-21 US disclosed
US-10836688-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose ABBVIE INC. (US) 2020-11-17 US disclosed
US-20140336190-A1 BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS GILEAD SCIENCES, INC. (US) 2014-11-13 US disclosed
US-20140336190-A1 BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS GILEAD SCIENCES, INC. (US) 2014-11-13 US disclosed
WO-2014176187-A1 PYRIDYLDIAMIDE METAL CATALYSTS AND PROCESSES TO PRODUCE POLYOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-10-30 WO disclosed
US-20140316089-A1 Pyridyldiamide Metal Catalysts and Processes to Produce Polyolefins EXXONMOBIL CHEMICAL PATENTS INC. 2014-10-23 US disclosed
US-8754241-B2 Organic compound and electrochromic element having the same CANON KABUSHIKI KAISHA (JP) 2014-06-17 US disclosed
US-20130190513-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-07-25 US disclosed
WO-2013060411-A1 HYPERBRANCHED POLYMERS, METHODS FOR PRODUCING SAME, AND USE OF SAME IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2013-05-02 WO disclosed
CN-100491323-C Biaryloxymethylarenecarboxylic acids compound HOFFMANN LA ROCHE (CH) 2009-05-27 CN disclosed
EP-1663936-B1 BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS HOFFMANN LA ROCHE (CH) 2008-01-09 EP disclosed
CN-1812956-A Biaryloxymethylarenecarboxylic acids as glycogen synthase activator HOFFMANN LA ROCHE (CH) 2006-08-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210017100-A1 ORGANIC REACTIONS CARRIED OUT IN AQUEOUS SOLUTION IN THE PRESENCE OF A HYDROXYALKYL(ALKYL)CELLULOSE OR AN ALKYLCELLULOSE LIPA, ALG1, CEL LPL 256/4885LIPG 120/4885IRAK4 3347/4885
US-20230279025-A1 KRAS G12D INHIBITORS KRAS, NRAS, HRAS LPL 4166/4885LIPG 3534/4885IRAK4 3902/4885
US-20130190513-A1 NOVEL ORGANIC COMPOUND AND ELECTROCHROMIC ELEMENT HAVING THE SAME EPB41, CNOT1, CYP4F11 LPL 4122/4885LIPG 3334/4885IRAK4 3566/4885
US-10836688-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose LIPA, ALG1, CEL LPL 256/4885LIPG 120/4885IRAK4 3347/4885
US-11312668-B2 Organic reactions carried out in aqueous solution in the presence of a hydroxyalkyl(alkyl)cellulose or an alkylcellulose LIPA, ALG1, CEL LPL 256/4885LIPG 120/4885IRAK4 3347/4885
US-20140336190-A1 BENZIMIDAZOLE DERIVATIVES AS BROMODOMAIN INHIBITORS BRD4, BRD3, BRD1 LPL 3456/4885LIPG 4316/4885IRAK4 970/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.