SCHEMBL5840223

SCHEMBL5840223

Cc1cccc(N)c1B1OC(C)(C)C(C)(C)O1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.47
CYP3A4 P08684 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
LPL P06858 8/20 0.38
LIPG Q9Y5X9 8/20 0.38
TSHR P16473 1/20 0.37
PIK3CA P42336 1/20 0.37
IRAK4 Q9NWZ3 1/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA9 Q16790 2/20 0.33
CA12 O43570 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
F11 P03951 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4674071 0.86 LPL (0.44) CD44LPLLIPGIRAK4CA1
SCHEMBL20788915 0.80 LPL (0.40) CD44CYP3A4LPLLIPGTSHR
SCHEMBL29225823 0.80 LIPG (0.37) CD44LPLLIPGIRAK4CA1
SCHEMBL29459939 0.80 LPL (0.40) CD44CYP3A4LPLLIPGTSHR
SCHEMBL22848280 0.80 ALDH1A1 (0.42) CD44CYP3A4LPLLIPGTSHR
SCHEMBL15542300 0.79 LPL (0.35) CD44CYP3A4TDP1LPLLIPG
SCHEMBL23301057 0.78 LPL (0.41) LPLLIPGIRAK4P2RX7
SCHEMBL20722870 0.78 LPL (0.38) LPLLIPGIRAK4ALDH1A1P2RX7
SCHEMBL18569315 0.78 LPL (0.38) LPLLIPGIRAK4ANPEPLAP3
SCHEMBL29897387 0.78 LPL (0.38) LPLLIPGIRAK4ALDH1A1P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260042791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-12 US disclosed
US-12281129-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-04-22 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-11737349-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-08-22 US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 US disclosed
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSITY DISPLAY CORPORATION (US) 2022-12-22 US disclosed
US-11440900-B2 Agricultural chemicals GLOBACHEM NV (BE) 2022-09-13 US disclosed
EP-3740474-B1 AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2022-01-05 EP disclosed
EP-3740474-B1 AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2022-01-05 EP disclosed
US-20150295192-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2015-10-15 US disclosed
WO-2015116885-A1 MACROCYCLES WITH AROMATIC P2' GROUPS AS FACTOR XIA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-08-06 WO disclosed
WO-2015116885-A1 MACROCYCLES WITH AROMATIC P2' GROUPS AS FACTOR XIA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-08-06 WO disclosed
US-7138530-B2 Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2006-11-21 US disclosed
US-7109354-B2 Thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2006-09-19 US disclosed
EP-1549632-A4 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS DIMENSIONAL PHARM INC (US) 2005-11-09 EP disclosed
US-20050234081-A1 Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions SUBASINGHE NALIN 2005-10-20 US disclosed
EP-1549632-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2005-07-06 EP disclosed
US-20040009995-A1 Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions 3-DIMENSIONAL PHARMACEUTICALS, INC. 2004-01-15 US disclosed
WO-2003099805-A1 NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2003-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150295192-A1 Organic Electroluminescent Materials and Devices PAXBP1, EML4, PAX2 CD44 3222/4885CYP3A4 1112/4885TDP1 2722/4885
US-20050234081-A1 Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions C5, C9, C1R CD44 3877/4885CYP3A4 1530/4885TDP1 4176/4885
US-20040009995-A1 Novel thiophene amidines, compositions thereof, and methods of treating complement-mediated diseases and conditions C5, C9, C1R CD44 4514/4885CYP3A4 1112/4885TDP1 3250/4885
US-11440900-B2 Agricultural chemicals NAT1, CYP51A1, NOS1 CD44 4552/4885CYP3A4 35/4885TDP1 1343/4885
US-12281129-B2 Organic electroluminescent materials and devices OCIAD1, OCIAD2, OSBP CD44 3247/4885CYP3A4 498/4885TDP1 2887/4885
US-11737349-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, OTC CD44 3807/4885CYP3A4 462/4885TDP1 2411/4885
US-20260042791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, GLRA1, MSL1 CD44 3556/4885CYP3A4 607/4885TDP1 4082/4885
US-20220402953-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP CD44 3247/4885CYP3A4 498/4885TDP1 2887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.