SCHEMBL467689

SCHEMBL467689

CO[Si](Br)(Cc1ccccc1)OC

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.39
TSHR P16473 4/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 1/20 0.39
TRPA1 O75762 1/20 0.39
CALM1 P0DP23 1/20 0.36
TDP1 Q9NUW8 2/20 0.36
IDO1 P14902 2/20 0.34
KDM4E B2RXH2 2/20 0.33
LOXL2 Q9Y4K0 1/20 0.33
AGXT P21549 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
MAOB P27338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3341648 0.76 TP53 (0.42) LTA4HTSHRALDH1A1TP53TRPA1
SCHEMBL2804442 0.76 TP53 (0.42) LTA4HTSHRALDH1A1TP53TRPA1
SCHEMBL104953 0.76 TP53 (0.42) LTA4HTSHRALDH1A1TP53TRPA1
SCHEMBL109029 0.74 TSHR (0.41) LTA4HTSHRALDH1A1TP53CALM1
SCHEMBL534142 0.74 TSHR (0.41) LTA4HTSHRALDH1A1TP53CALM1
SCHEMBL15301959 0.73 TSHR (0.43) TSHRALDH1A1TP53TRPA1CALM1
SCHEMBL2202415 0.73 LTA4H (0.39) LTA4HTSHRALDH1A1TP53CALM1
Methylamine SCHEMBL29141165 0.73 IDO1 (0.39) LTA4HTSHRALDH1A1TP53CALM1
SCHEMBL9505647 0.73 LTA4H (0.39) LTA4HTSHRALDH1A1TP53TRPA1
SCHEMBL534035 0.73 TP53 (0.44) LTA4HTSHRALDH1A1TP53TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2386561-B1 Methods for producing alkoxyhydrosilanes KANEKA CORP (JP) 2016-01-13 EP disclosed
EP-2392600-B1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer KANEKA CORP (JP) 2015-12-23 EP disclosed
EP-2586784-B1 METHOD FOR PRODUCING ALKOXY HYDROSILANE KANEKA CORP (JP) 2015-12-09 EP disclosed
EP-2586783-B1 METHOD FOR PRODUCING ALKOXY HYDROSILANE KANEKA CORP (JP) 2015-08-05 EP disclosed
EP-2586783-A1 METHOD FOR PRODUCING ALKOXY HYDROSILANE Kaneka Corporation (JP) 2013-05-01 EP disclosed
EP-2586784-A1 METHOD FOR PRODUCING ALKOXY HYDROSILANE Kaneka Corporation (JP) 2013-05-01 EP disclosed
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF KANEKACORPORATION (JP) 2012-08-02 US disclosed
EP-2392600-A1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer Kaneka Corporation (JP) 2011-12-07 EP disclosed
EP-2386561-A1 Methods for producing alkoxyhydrosilanes Kaneka Corporation (JP) 2011-11-16 EP disclosed
US-8039142-B2 Battery case SONY CORPORATION (JP) 2011-10-18 US disclosed
US-20110207886-A1 Method for Producing a-hereto-Substituted Alkylhalohydrosilane and Use Thereof KANEKA CORPORATION (JP) 2011-08-25 US disclosed
EP-2308884-A1 METHOD FOR PRODUCING -HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF Kaneka Corporation (JP) 2011-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF ARSA, HACL2, AS3MT LTA4H 2608/4885TSHR 3146/4885ALDH1A1 2288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.