SCHEMBL467777

SCHEMBL467777

O=c1cc(O)c2ccccc2s1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.55
ALOX15 P16050 1/20 0.55
MAOB P27338 2/20 0.50
MAOA P21397 1/20 0.50
GPR3 P46089 1/20 0.46
POLB P06746 4/20 0.44
MAPT P10636 4/20 0.44
LMNA P02545 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
HCRTR1 O43613 1/20 0.44
TRPM4 Q8TD43 1/20 0.43
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
GAA P10253 1/20 0.42
CA12 O43570 2/20 0.42
CA9 Q16790 2/20 0.42
KDM4E B2RXH2 2/20 0.42
CA1 P00915 1/20 0.41
MAPK1 P28482 1/20 0.41
RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30819315 1.00 ALDH1A1 (0.55) ALDH1A1ALOX15MAOBMAOAGPR3
SCHEMBL10619559 0.75 ALDH1A1 (0.55) ALDH1A1ALOX15MAOBGPR3POLB
SCHEMBL2473539 0.75 BCKDK (0.46) ALDH1A1POLBMAPTLMNACA9
SCHEMBL2472396 0.74 MAOA (0.46) ALDH1A1ALOX15MAOBMAOAPOLB
SCHEMBL5713277 0.72 ALDH1A1 (0.47) ALDH1A1ALOX15GPR3POLBMAPT
SCHEMBL2471786 0.72 CYP1A1 (0.50) POLBMAPTTRPM4KDM4ENPSR1
SCHEMBL466086 0.71 ALDH1A1 (1.00) ALDH1A1ALOX15MAOBMAOAGPR3
SCHEMBL31676779 0.71 KDM4E (0.59) ALDH1A1ALOX15MAOBMAOAGPR3
SCHEMBL21624260 0.71 KDM4E (0.59) ALDH1A1ALOX15MAOBMAOAGPR3
SCHEMBL2475121 0.69 ALDH1A1 (0.38) ALDH1A1MAOBMAOAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0161163-B1 4-HYDROXY-2H-1-BENZOTHIOPYRAN-2-ONE DERIVATIVES, THEIR PREPARATION AND USES LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1987-09-23 EP claimed
WO-2026087745-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-30 WO disclosed
EP-4732825-A1 AN ANTIOXIDANT COMPOSITION COMPRISING A CINNAMIC ACID DERIVATIVE BRAIN Biotech AG (DE) 2026-04-29 EP disclosed
EP-4580594-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS AnalytiCon Discovery - Zweigniederlassung der BRAIN Biotech AG (DE) 2025-07-09 EP disclosed
US-20240142665-A1 OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2024-05-02 US disclosed
WO-2024046834-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS ANALYTICON DISCOVERY GMBH (DE) 2024-03-07 WO disclosed
EP-4331564-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS Analyticon Discovery GmbH (DE) 2024-03-06 EP disclosed
EP-4263513-A1 OPTICALLY ACTIVE DEVICES AMO Ireland (IE) 2023-10-25 EP disclosed
US-20230165242-A1 RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS LIPHATECH INC (FR) 2023-06-01 US disclosed
CN-113150006-B Pyran compound and synthetic method thereof 五邑大学 2022-07-05 CN disclosed
EP-0644198-A1 Alpha-heteroaryloxymethyl ketones as interleukin-1beta converting enzyme inhibitors STERLING WINTHROP INC. (US) 1995-03-22 EP disclosed
US-5382572-A Viricides SCHERING CORPORATION (US) 1995-01-17 US disclosed
EP-0547145-A1 ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS SCHERING CORPORATION (US) 1993-06-23 EP disclosed
EP-0539372-A1 THERAPEUTIC AGENTS The Boots Company PLC (GB) 1993-05-05 EP disclosed
WO-1992004326-A1 ANTIVIRAL COMPOUNDS SCHERING CORPORATION (US) 1992-03-19 WO disclosed
WO-1991011448-A1 THERAPEUTIC AGENTS THE BOOTS COMPANY PLC (GB) 1991-08-08 WO disclosed
US-4957931-A ANTICONVULSANTS, TREATMENT OF EPILEPSY CIBA-GEIGY CORPORATION (US) 1990-09-18 US disclosed
US-4859691-A Certain 1,2-benzisoxazole derivatives CIBA-GEIGY CORPORATION (US) 1989-08-22 US disclosed
US-4585786-A Rodenticidal 4-hydroxy-2H-1-benzothiopyran-2-one derivatives, compositions, and method of use therefor LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1986-04-29 US disclosed
EP-0161163-A1 4-Hydroxy-2H-1-benzothiopyran-2-one derivatives, their preparation and uses LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1985-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165242-A1 RODENTICIDAL BAIT AND METHOD OF CONTROLLING TARGET HARMFUL RODENTS VDR, CYP2R1, CYP24A1 ALDH1A1 3777/4885ALOX15 1560/4885MAOB 4826/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.