Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | NPY1R | P25929 | 1/20 | 0.58 |
| ▸ | NPY2R | P49146 | 1/20 | 0.58 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165382 | 0.94 | MMP8 (0.76) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL28682225 | 0.89 | MMP8 (0.69) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL856250 | 0.89 | MMP8 (0.69) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL5713294 | 0.88 | MMP8 (0.68) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL6893163 | 0.88 | MMP8 (0.68) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL3797033 | 0.87 | MMP8 (0.62) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL27385612 | 0.87 | LMNA (0.65) | MMP8ALDH1A1L3MBTL1LMNAPPARG | |
| SCHEMBL13699115 | 0.86 | MMP8 (0.66) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL5143414 | 0.86 | MMP8 (0.66) | MMP8ALDH1A1TP53NPY1RNPY2R | |
| SCHEMBL8329377 | 0.86 | MMP8 (0.66) | MMP8ALDH1A1TP53NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110283103-B | Method for synthesizing α amino acid ester/amide by base-catalyzed decarboxylation amination | 北京理工大学 | 2020-08-04 | — | — | CN | claimed |
| US-20250346613-A1 | BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF | ARTIVILA BIOPHARMA (CN) | 2025-11-13 | — | — | US | disclosed |
| US-20250170104-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-05-29 | — | — | US | disclosed |
| EP-4516796-A1 | BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF | Artivila Biopharma (CN) | 2025-03-05 | — | — | EP | disclosed |
| EP-4486452-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASSS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-01-08 | — | — | EP | disclosed |
| US-12152023-B2 | Compositions, formulations and methods for treating ocular diseases | EyePoint Pharmaceuticals, Inc. (US) | 2024-11-26 | — | — | US | disclosed |
| CN-117003776-A | Boric acid proteasome inhibitor and application thereof | 科辉智药生物科技(深圳)有限公司 | 2023-11-07 | — | — | CN | disclosed |
| WO-2023207889-A1 | BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF | 科辉智药生物科技（无锡）有限公司 | 2023-11-02 | — | — | WO | disclosed |
| WO-2023166039-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |
| WO-2023166039-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-09-07 | — | — | WO | disclosed |
| WO-1992021361-A1 | TERMINALLY MODIFIED TRI-, TETRA- AND PENTAPEPTIDE ANAPHYLATOXIN RECEPTOR LIGANDS | ABBOTT LABORATORIES (US) | 1992-12-10 | — | — | WO | disclosed |
| EP-0417698-A2 | Amino acid derivatives having renin-inhibiting activity, process for their preparation, agents containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-03-20 | — | — | EP | disclosed |
| CN-1048039-A | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORP (US) | 1990-12-26 | — | — | CN | disclosed |
| CN-1048038-A | IMIDAZOLYL-ALKENOIC ACIDS | SMITHKLINE BEECHAM CORP (US) | 1990-12-26 | — | — | CN | disclosed |
| EP-0403158-A2 | Imidazolyl-alkenoic acids | SMITHKLINE BEECHAM CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0127235-B1 | PARTIALLY RETRO-INVERTED DECAPEPTIDE AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS | ENI-Ente Nazionale Idrocarburi (IT) | 1988-10-19 | — | — | EP | disclosed |
| US-4738803-A | ENZYME INHIBITORS | ROQUES BERNARD (FR) | 1988-04-19 | — | — | US | disclosed |
| US-4618708-A | ENKEPHALINASE INHIBITOR, ANALGESICS, ANTIDEPRESSANT, ANTIDIARRHEA, OR HYPOTENSIVE AGENT | ROQUES BERNARD (FR) | 1986-10-21 | — | — | US | disclosed |
| US-4585586-A | HYPOTENSIVE | ENTE NAZIONALE IDROCARBURI (IT) | 1986-04-29 | — | — | US | disclosed |
| EP-0127235-A2 | Partially retro-inverted decapeptide as a specific renin inhibitor with high resistance to enzymatic hydrolysis | ENI-Ente Nazionale Idrocarburi (IT) | 1984-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250346613-A1 | BORIC ACID PROTEASOME INHIBITOR AND USE THEREOF | PSMA1, PSMB11, PSMB1 | MMP8 3925/4885ALDH1A1 2948/4885TP53 876/4885 |
| US-20250170104-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR Lasß | LTA, SERPINB1, LAS1L | MMP8 95/4885ALDH1A1 3061/4885TP53 1612/4885 |
| US-12152023-B2 | Compositions, formulations and methods for treating ocular diseases | TIE1, TEK, KDR | MMP8 1563/4885ALDH1A1 3657/4885TP53 3257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.