SCHEMBL4679934

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4680464	0.91	ALDH1A1 (0.45)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL159668	0.86	SMN1; SMN2 (0.50)	ALDH1A1FFAR1TP53TSHRSMN1; SMN2
	SCHEMBL4680444	0.85	ALDH1A1 (0.44)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL4683108	0.82	ALDH1A1 (0.42)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL4681298	0.80	ALDH1A1 (0.48)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL18782519	0.80	ALDH1A1 (0.54)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL18381104	0.80	ALDH1A1 (0.54)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL31329304	0.79	ALOX5 (0.55)	ALDH1A1L3MBTL1KMT2ATP53TSHR
	SCHEMBL18381100	0.78	ALDH1A1 (0.53)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1
	SCHEMBL5353557	0.78	ALDH1A1 (0.42)	ALDH1A1MAPK1L3MBTL1KMT2AFFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.