Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | SLC15A1 | P46059 | 2/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9193055 | 0.91 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1TRPA1SLC15A1 | |
| SCHEMBL28769441 | 0.87 | TRPA1 (0.51) | ALDH1A1MAPK1L3MBTL1TRPA1TRPV1 | |
| SCHEMBL4747934 | 0.87 | TRPA1 (0.51) | ALDH1A1MAPK1L3MBTL1TRPA1SLC15A1 | |
| SCHEMBL667948 | 0.87 | TRPA1 (0.51) | ALDH1A1MAPK1L3MBTL1TRPA1SLC15A1 | |
| SCHEMBL22033657 | 0.87 | ALDH1A1 (0.50) | ALDH1A1MAPK1L3MBTL1TRPA1SLC15A1 | |
| SCHEMBL6153568 | 0.85 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1SLC15A1LMNA | |
| SCHEMBL6369826 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1TRPA1SLC15A1 | |
| SCHEMBL29233259 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPK1L3MBTL1SLC15A1CASP1 | |
| SCHEMBL20966571 | 0.84 | GPR84 (0.51) | ALDH1A1MAPK1L3MBTL1TRPA1TRPV1 | |
| SCHEMBL22033713 | 0.84 | GPR84 (0.51) | ALDH1A1MAPK1L3MBTL1TRPA1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594853-B1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | claimed |
| US-7371854-B2 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | claimed |
| US-20060142568-A1 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MEREK PATENT GMBH (DE) | 2006-06-29 | — | — | US | claimed |
| US-7371854-B2 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-20060142568-A1 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MEREK PATENT GMBH (DE) | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060142568-A1 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | ITGA1, ITGB1, ITGA2 | ALDH1A1 695/4885MAPK1 944/4885L3MBTL1 4065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.