Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.36 |
| ▸ | ATP4B | P51164 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2301856 | 0.82 | ALDH1A1 (0.50) | MAPTALDH1A1NPSR1TSHRATP4A | |
| SCHEMBL17628672 | 0.75 | HTT (0.54) | MAPTALDH1A1NPSR1CDC25BDUSP3 | |
| SCHEMBL4724668 | 0.74 | SOAT1 (0.43) | GPR84MAPTALDH1A1NPSR1ATP4A | |
| SCHEMBL3185311 | 0.74 | CALM1 (0.39) | MAPTALDH1A1TSHR | |
| SCHEMBL11994166 | 0.73 | GPR84 (0.43) | GPR84HSD11B1MAPTALDH1A1NPSR1 | |
| SCHEMBL329947 | 0.73 | HSD11B1 (0.40) | GPR84HSD11B1MAPTALDH1A1TSHR | |
| SCHEMBL11994177 | 0.72 | ATP4A (0.58) | MAPTALDH1A1NPSR1ATP4AATP4B | |
| SCHEMBL11994165 | 0.72 | ALDH1A1 (0.47) | GPR84MAPTALDH1A1ATP4AATP4B | |
| SCHEMBL2398613 | 0.71 | HSD11B1 (0.51) | HSD11B1MAPTALDH1A1TSHRHSD17B10 | |
| SCHEMBL10475629 | 0.71 | ALDH1A1 (0.71) | GPR84MAPTALDH1A1ATP4AATP4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385763-A1 | METHODS FOR TREATING VASCULAR LEAK SYNDROME | Akebia Therapeutics Inc. (US) | 2011-11-16 | — | — | EP | disclosed |
| US-20110253725-A1 | MULTI-PORT BEVERAGE AND FOOD CONTAINERS | KILLIAN WILLIAM | 2011-10-20 | — | — | US | disclosed |
| WO-2011005330-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS FOR PREVENTING METASTASIS OF CANCER CELLS | AKEBIA THERAPEUTICS INC. (US) | 2011-01-13 | — | — | WO | disclosed |