Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288664 | 0.89 | TBXAS1 (0.33) | TAAR1ALOX15TXNRD1FDPSALDH1A1 | |
| SCHEMBL4681643 | 0.85 | TBXAS1 (0.35) | TAAR1ALOX15TXNRD1TBXAS1 | |
| SCHEMBL7296081 | 0.85 | TBXAS1 (0.35) | TAAR1ALOX15TXNRD1TBXAS1 | |
| SCHEMBL4686081 | 0.83 | ALDH1A1 (0.34) | TAAR1ALOX15TXNRD1FDPSALDH1A1 | |
| SCHEMBL4682206 | 0.82 | CA2 (0.36) | TAAR1ALOX15TXNRD1FDPSALDH1A1 | |
| SCHEMBL7288670 | 0.79 | CA2 (0.40) | TAAR1ALOX15TXNRD1FDPSTBXAS1 | |
| SCHEMBL2010779 | 0.79 | ALDH1A1 (0.39) | TAAR1ALOX15TXNRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2851629 | 0.78 | EPHX2 (0.39) | TAAR1TXNRD1HTR1A | |
| SCHEMBL4686083 | 0.78 | TBXAS1 (0.36) | ALOX15TXNRD1FDPSALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4002548 | 0.77 | TAAR1 (0.34) | TAAR1ALOX15TXNRD1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |