Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | TXN | P10599 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686081 | 0.83 | ALDH1A1 (0.34) | ALDH1A1SMN1; SMN2TXNRD1TAAR1HTR1A | |
| SCHEMBL2851629 | 0.81 | EPHX2 (0.39) | TXNRD1TAAR1HTR1ACYP1A2CYP3A4 | |
| SCHEMBL4686083 | 0.81 | TBXAS1 (0.36) | ALDH1A1SMN1; SMN2TXNRD1KDM4EALOX15 | |
| SCHEMBL4682203 | 0.79 | TAAR1 (0.33) | ALDH1A1SMN1; SMN2TXNRD1TAAR1HTR1A | |
| SCHEMBL4684150 | 0.79 | TXNRD1 (0.33) | ALDH1A1SMN1; SMN2TXNRD1TAAR1TXN | |
| SCHEMBL4682206 | 0.78 | CA2 (0.36) | ALDH1A1SMN1; SMN2TXNRD1TAAR1HTR1A | |
| Hydrochloric Acid SCHEMBL4005242 | 0.77 | TXNRD1 (0.33) | ALDH1A1SMN1; SMN2TXNRD1TAAR1TXN | |
| SCHEMBL7360834 | 0.77 | TXNRD1 (0.33) | ALDH1A1SMN1; SMN2TXNRD1TAAR1TXN | |
| SCHEMBL11071751 | 0.77 | TXNRD1 (0.38) | ALDH1A1SMN1; SMN2TXNRD1TXNKDM4E | |
| SCHEMBL4684154 | 0.77 | FDPS (0.36) | ALDH1A1SMN1; SMN2TXNRD1TAAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101362755-B | Sulfosulfuron preparation method | JIANGSU AGROCHEM LAB | 2012-01-11 | — | — | CN | claimed |
| CN-101362755-A | Sulfosulfuron preparation method | JIANGSU AGRICULTURAL HORMONE E (CN) | 2009-02-11 | — | — | CN | claimed |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | BioVersys AG (CH) | 2018-04-05 | — | — | US | disclosed |
| EP-1934238-B1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | MELINTA THERAPEUTICS INC (US) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016172631-A2 | SUBSTRATE SELECTIVE INHIBITORS OF INSULIN-DEGRADING ENZYME (IDE) AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-10-27 | — | — | WO | disclosed |
| US-20160031926-A1 | Triazole Compounds and Methods of Making and Using the Same | BioVersys AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-20160031926-A1 | Triazole Compounds and Methods of Making and Using the Same | BioVersys AG (CH) | 2016-02-04 | — | — | US | disclosed |
| US-9006189-B2 | Triazole compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-9006189-B2 | Triazole compounds and methods of making and using the same | MELINTA THERAPEUTICS, INC. (US) | 2015-04-14 | — | — | US | disclosed |
| US-20140088031-A1 | Triazole Compounds and Methods of Making and Using the Same | RIB-X PHARMACEUTICALS, INC. (US) | 2014-03-27 | — | — | US | disclosed |
| US-20100016956-A1 | Triazole compounds and methods of making and using the same | BioVersys AG (CH) | 2010-01-21 | — | — | US | disclosed |
| CN-101362755-A | Sulfosulfuron preparation method | JIANGSU AGRICULTURAL HORMONE E (CN) | 2009-02-11 | — | — | CN | disclosed |
| WO-2008143730-A2 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008106224-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008106204-A1 | MACROLIDE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X-PHARMACEUTICALS, INC. (US) | 2008-09-04 | — | — | WO | disclosed |
| WO-2008091475-A1 | SULFONYL GRAFTED HETEROCYCLE MATERIALS FOR PROTON CONDUCTING ELECTROLYTES | TOYOTA MOTOR ENGINERING & MANUFACTURING NORTH AMERICA, INC. (US) | 2008-07-31 | — | — | WO | disclosed |
| CN-101230113-A | Sulfonyl grafted heterocycle materials for proton conducting electrolytes | TOYOTA MOTOR ENGINERING & MFG (US) | 2008-07-30 | — | — | CN | disclosed |
| US-20080152985-A1 | SULFONYL GRAFTED HETEROCYCLE MATERIALS FOR PROTON CONDUCTING ELECTROLYTES | Toyota Engineering & Manufacturing North America, Inc. (US) | 2008-06-26 | — | — | US | disclosed |
| WO-2007025284-A1 | TRIAZOLE COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | RIB-X PHARMACEUTICALS, INC. (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016956-A1 | Triazole compounds and methods of making and using the same | IL33, PROKR1, PGC | ALDH1A1 3557/4885SMN1; SMN2 4620/4885TXNRD1 1076/4885 |
| US-20180094016-A1 | Triazole Compounds And Methods Of Making And Using The Same | IL33, PROKR1, VIP | ALDH1A1 3532/4885SMN1; SMN2 4598/4885TXNRD1 1264/4885 |
| US-20160031926-A1 | Triazole Compounds and Methods of Making and Using the Same | IL33, PROKR1, VIP | ALDH1A1 3532/4885SMN1; SMN2 4598/4885TXNRD1 1264/4885 |
| US-20140088031-A1 | Triazole Compounds and Methods of Making and Using the Same | IL33, PROKR1, VIP | ALDH1A1 3532/4885SMN1; SMN2 4598/4885TXNRD1 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.