Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 4/20 | 0.40 |
| ▸ | LCK | P06239 | 3/20 | 0.40 |
| ▸ | MET | P08581 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4233515 | 0.90 | HTR4 (0.43) | KMT2AMEN1KDRLCKMET | |
| SCHEMBL4229335 | 0.80 | KMT2A (0.37) | KMT2AMEN1KDRLCKMET | |
| SCHEMBL4233458 | 0.77 | ADRB2 (0.46) | KMT2AMEN1ADRB2 | |
| SCHEMBL4242398 | 0.74 | MAOA (0.41) | KMT2AMEN1ADRB2 | |
| SCHEMBL4850647 | 0.74 | KDR (0.35) | KDRLCKMETFGFR1CCR3 | |
| SCHEMBL4227016 | 0.72 | MAOA (0.42) | HRH3KMT2AMEN1ADRB2 | |
| SCHEMBL4240285 | 0.72 | ADRB2 (0.45) | KMT2AMEN1CCR3ADRB2 | |
| SCHEMBL4239009 | 0.67 | MAOA (0.44) | HRH3KMT2AMEN1ADRB2 | |
| SCHEMBL4231930 | 0.67 | MEN1 (0.41) | KMT2AMEN1 | |
| SCHEMBL4240130 | 0.66 | ACHE (0.38) | HRH3KMT2AMEN1GAAFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |