Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.71 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.71 |
| ▸ | HTR1A | P08908 | 2/20 | 0.71 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 14/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.58 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.55 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271352 | 0.89 | ADRB2 (0.69) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL29866225 | 0.89 | ADRB2 (0.69) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL593753 | 0.89 | ADRB2 (0.69) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL593754 | 0.89 | ADRB2 (0.69) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL721150 | 0.89 | ADRB2 (0.69) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL27657195 | 0.89 | ADRB2 (0.69) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL3723459 | 0.85 | ADRB1 (0.77) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL8855337 | 0.83 | ADRB2 (0.82) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| SCHEMBL11817096 | 0.83 | ADRB2 (0.83) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 | |
| Sulfinalol SCHEMBL29387627 | 0.83 | SLC6A4 (0.66) | ADRA1ASLC6A4HTR1ASLC6A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7462645-B2 | Bronchodilating beta-agonist compositions and methods | JPMORGAN CHASE BANK, N.A. (US) | 2008-12-09 | — | — | US | disclosed |