Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14102482 | 0.86 | NOS1 (0.49) | TRPV1AXL | |
| Hydrochloric Acid SCHEMBL4683856 | 0.85 | NOS1 (0.47) | TRPV1AXL | |
| SCHEMBL22619200 | 0.75 | NOS1 (0.44) | TRPV1AXL | |
| SCHEMBL7775075 | 0.73 | HTR2A (0.43) | TRPV1AXL | |
| Trifluoroacetic Acid SCHEMBL28221732 | 0.71 | HTR2C (0.47) | TRPV1 | |
| SCHEMBL17739153 | 0.69 | CREBBP (0.56) | TRPV1 | |
| Indazole SCHEMBL2267425 | 0.68 | HSP90AA1 (0.66) | AXL | |
| Indazole SCHEMBL20239569 | 0.68 | HSP90AA1 (0.66) | AXL | |
| Indazole SCHEMBL29627950 | 0.68 | HSP90AA1 (0.66) | AXL | |
| Indazole SCHEMBL2267429 | 0.68 | HSP90AA1 (0.66) | AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753763-B1 | INDAZOLE AND INDOLONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | PFIZER LTD (GB) | 2008-08-13 | — | — | EP | disclosed |
| EP-1753763-A2 | INDAZOLE AND INDOLONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Pfizer Limited (GB) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005116027-A2 | INDAZOLE AND INDOLONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | PFIZER LIMTED (GB) | 2005-12-08 | — | — | WO | disclosed |
| US-20050267096-A1 | New indazole and indolone derivatives and their use pharmaceuticals | PFIZER INC | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050267096-A1 | New indazole and indolone derivatives and their use pharmaceuticals | DRD2, DRD3, DRD1 | TRPV1 1329/4885AXL 2523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.