Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.33 |
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | BCL9 | O00512 | 3/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | KIT | P10721 | 2/20 | 0.31 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | SLC34A2 | O95436 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741711 | 0.92 | SSTR5 (0.36) | CCR5DRD2ADRA1AGHSRP2RY1 | |
| SCHEMBL4687968 | 0.90 | DRD2 (0.37) | CCR5DRD2ADRA1AGHSRP2RY1 | |
| SCHEMBL4232938 | 0.83 | BCL9 (0.43) | BCL9CTNNB1 | |
| SCHEMBL4238698 | 0.82 | CCR5 (0.47) | CCR5LTA4HMCHR1LMNA | |
| SCHEMBL4741379 | 0.79 | DDR2 (0.34) | BCL9CTNNB1 | |
| SCHEMBL4744081 | 0.78 | MCHR1 (0.38) | CCR5MCHR1 | |
| SCHEMBL4238724 | 0.78 | MCHR1 (0.37) | DRD2ADRA1ABCL9CTNNB1MCHR1 | |
| SCHEMBL4236545 | 0.77 | MCHR1 (0.34) | DRD2ADRA1ABCL9CTNNB1MCHR1 | |
| SCHEMBL4232410 | 0.76 | PKM (0.39) | — | |
| SCHEMBL4228379 | 0.75 | MCHR1 (0.41) | CCR5MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |