SCHEMBL468827

SCHEMBL468827

C=C(C)C(=O)NCOC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
HSD17B10 Q99714 2/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 4/20 0.37
THRB P10828 1/20 0.36
TGFBR1 P36897 1/20 0.35
TDP1 Q9NUW8 2/20 0.33
FAAH O00519 1/20 0.32
CHRM5 P08912 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
PGR P06401 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16803338 0.86 ALDH1A1 (0.42) ALDH1A1TSHRTHRBTGFBR1TDP1
SCHEMBL17250046 0.84 THRB (0.48) ALDH1A1TSHRTHRBTGFBR1TDP1
SCHEMBL2346839 0.81 ALDH1A1 (0.40) ALDH1A1HSD17B10TSHRTHRBTGFBR1
SCHEMBL28012791 0.81 TGFBR1 (0.36) ALDH1A1TSHRTHRBTGFBR1GAA
SCHEMBL9845188 0.81 MGAM (0.38) ALDH1A1HSD17B10LMNATSHRTHRB
SCHEMBL13275582 0.81 MGAM (0.43) ALDH1A1TSHRTHRBTGFBR1GAA
SCHEMBL28198324 0.79 TSHR (0.45) ALDH1A1HSD17B10TSHRTHRBTGFBR1
SCHEMBL339706 0.79 TSHR (0.38) ALDH1A1TSHRTHRBTGFBR1
SCHEMBL28123693 0.79 PRKCA (0.34) ALDH1A1TSHRTHRBTGFBR1GAA
SCHEMBL30806 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102282026-B Rubber mixtures containing silane and having possibly functionalized diene rubbers and microgels, a method for the production thereof, and use thereof LANXESS DEUTSCHLAND GMBH 2014-07-09 CN claimed
US-8399105-B2 Polymer latex suitable for the preparation of dip-molded articles POLYMER LATEX GMBH & CO., KG (DE) 2013-03-19 US claimed
US-20120028525-A1 POLYMER LATEX SUITABLE FOR THE PREPARATION OF DIP-MOLDED ARTICLES POLYMER LATEX GMBH & CO. KG (DE) 2012-02-02 US claimed
US-7604031-B2 Pneumatic tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 2009-10-20 US claimed
EP-1789457-B9 POLYMER LATEX SUITABLE FOR THE PREPARATION OF DIP-MOLDED ARTICLES POLYMERLATEX GMBH (DE) 2008-11-26 EP claimed
US-20080149245-A1 Pneumatic Tire THIELEN GEORGES MARCEL VICTOR 2008-06-26 US claimed
US-20080149248-A1 Comprised of a rubber containing olefinic unsaturation, silica and polyoctenamer; abrasion resistance; improved rolling resistance; improved 300% modulus is correlated with improved sidewall performance, and improved abrasion resistance is desirable for improved sidewall durability THE GOODYEAR TIRE & RUBBER COMPANY 2008-06-26 US claimed
EP-1935668-A2 Pneumatic tire THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-06-25 EP claimed
EP-1935926-A1 Process of preparing a rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 2008-06-25 EP claimed
US-20080114108-A1 Pneumatic tire FRANK UWE ERNST 2008-05-15 US claimed
EP-1634894-A1 Polymer latex suitable for the preparation of dip-molded articles PolymerLatex GmbH (DE) 2006-03-15 EP claimed
US-20060052513-A1 Polymer latex suitable for the preparation of dip-molded articles POLYMER LATEX GMBH & CO. KG (DE) 2006-03-09 US claimed
EP-1241219-B1 Pneumatic tire having a rubber component containing a rubber gel, a syndiotactic 1,2-Polybutadiene and an olefinically unsaturated rubber GOODYEAR TIRE & RUBBER (US) 2005-05-11 EP claimed
US-6848487-B2 Pneumatic tire having a rubber component containing a rubber gel and starch composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2005-02-01 US claimed
US-6807994-B2 COMBINING A LOW LEVEL IN HYSTERESIS WITH HIGH DYNAMIC STIFFNESS THE GOODYEAR TIRE & RUBBER COMPANY 2004-10-26 US claimed
US-20040122134-A1 Pneumatic tire having a rubber component containing a rubber gel and starch composite GOODYEAR TIRE & RUBBER COMPANY, THE 2004-06-24 US claimed
EP-1431075-A1 Pneumatic tire having a rubber component containing a rubber gel and starch composite THE GOODYEAR TIRE & RUBBER COMPANY (US) 2004-06-23 EP claimed
US-20020170642-A1 Pneumatic tire having a rubber component containing a rubber gel and syndiotatic 1,2-polybutadiene GOODYEAR TIRE & RUBBER COMPANY, THE 2002-11-21 US claimed
EP-1241219-A1 Pneumatic tire having a rubber component containing a rubber gel, a syndiotactic 1,2-Polybutadiene and an olefinically unsaturated rubber THE GOODYEAR TIRE & RUBBER COMPANY (US) 2002-09-18 EP claimed
US-5043363-A Active energy ray-curing resin composition CANON KABUSHIKI KAISHA (JP) 1991-08-27 US claimed