Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL339532 | 0.81 | MEN1 (0.46) | TSHRMEN1KMT2ATGFBR1RXFP1 | |
| SCHEMBL18808392 | 0.81 | TGFBR1 (0.33) | TSHRTGFBR1THRBALDH1A1 | |
| SCHEMBL784654 | 0.80 | TGFBR1 (0.40) | TSHRTGFBR1RXFP1THRB | |
| SCHEMBL468827 | 0.79 | ALDH1A1 (0.39) | TSHRTGFBR1THRBALDH1A1 | |
| SCHEMBL16803338 | 0.79 | ALDH1A1 (0.42) | TSHRTGFBR1THRBALDH1A1 | |
| SCHEMBL18007139 | 0.79 | TGFBR1 (0.35) | TSHRTGFBR1 | |
| SCHEMBL340563 | 0.79 | ALDH1A1 (0.41) | TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL17250046 | 0.78 | THRB (0.48) | TSHRTGFBR1THRBALDH1A1 | |
| SCHEMBL339839 | 0.77 | TSHR (0.35) | TSHRMEN1KMT2ATGFBR1RXFP1 | |
| SCHEMBL855074 | 0.76 | TGFBR1 (0.37) | TSHRMEN1KMT2ATGFBR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | UNIVERSITEIT UTRECHT (NL) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015034-A1 | TEMPERATURE SENSITIVE POLYMERS | LCT, LDHA, LDHB | TSHR 4451/4885MEN1 3434/4885KMT2A 2446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.