Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | PNLIP | P16233 | 5/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ESRRA | P11474 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | PARG | Q86W56 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683259 | 0.87 | PKM (0.49) | PKMNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL4744588 | 0.87 | PKM (0.57) | PKMNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL4231850 | 0.86 | PKM (0.48) | PKMNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL4688997 | 0.83 | EPHX2 (0.55) | NPC1RAB9ASMN1; SMN2PNLIPHTT | |
| SCHEMBL4236606 | 0.80 | PKM (0.56) | PKMPNLIPMAPTESRRAMEN1 | |
| SCHEMBL4238208 | 0.80 | PKM (0.53) | PKMTAS1R3TAS1R1PNLIPMAPT | |
| SCHEMBL4240850 | 0.80 | PKM (0.53) | PKMTAS1R3TAS1R1PNLIPMAPT | |
| SCHEMBL4228783 | 0.78 | PKM (0.41) | PKMNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL4226808 | 0.77 | CCR3 (0.40) | PKMNPC1RAB9ASMN1; SMN2KDR | |
| SCHEMBL4233787 | 0.77 | PKM (0.56) | PKMRAB9ATAS1R3TAS1R1PDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |