SCHEMBL4691097

SCHEMBL4691097

CCC(Cl)N1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4931478 0.97 SLC6A3 (0.35)
SCHEMBL4294178 0.97 SLC6A3 (0.35)
Hydrochloric Acid SCHEMBL1622048 0.95 SLC6A4 (0.34)
SCHEMBL27128838 0.94
SCHEMBL9114190 0.79 CHRM2 (0.34)
SCHEMBL5605219 0.79 OPRD1 (0.37)
SCHEMBL28790729 0.79
SCHEMBL28205449 0.79 SLC6A3 (0.37)
SCHEMBL3707777 0.77 ALDH1A1 (0.39)
Hydrochloric Acid SCHEMBL5219661 0.75 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1828125-B1 ARYLPIPERAZINE DERIVATIVES AND THEIR USE AS LIGANGS SELECTIVE OF THE DOPAMINE D3 RECEPTOR BIOPROJET SOC CIV (FR) 2008-04-09 EP disclosed
EP-1828125-A1 ARYLPIPERAZINE DERIVATIVES AND THEIR USE AS LIGANGS SELECTIVE OF THE DOPAMINE D3 RECEPTOR BIOPROJET (FR) 2007-09-05 EP disclosed
US-7205311-B2 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED 2007-04-17 US disclosed
WO-2006058993-A1 ARYLPIPERAZINE DERIVATIVES AND THEIR USE AS LIGANDS SELECTIVE OF THE DOPAMINE D3 RECEPTOR BIOPROJET (FR) 2006-06-08 WO disclosed
US-20050070568-A1 Therapeutic acridone and acridine compounds CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2005-03-31 US disclosed
EP-1474397-A1 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS Cancer Research Technology Limited (GB) 2004-11-10 EP disclosed
WO-2003059885-A1 THERAPEUTIC ACRIDONE AND ACRIDINE COMPOUNDS CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2003-07-24 WO disclosed
EP-0894800-B1 Aliphatic solutions of aminoalkyllithium compounds BRIDGESTONE CORP (JP) 2003-03-12 EP disclosed
US-6046288-A REDUCING ALIPHATIC SOLVENT AMOUNT NEEDED FOR MAINTAINING AMINOALKYLLITHIUM INITIATORS IN SOLUTION BY COMBINING A CYCLIC AMINOALKYLLITHIUM COMPOUND OF GIVEN FORMULA WITH A DISSIMILAR LITHIOAMINE USEFUL IN ANIONIC POLYMERIZATION BRIDGESTONE CORPORATION (JP) 2000-04-04 US disclosed
US-5935893-A MIXTURE CONTAINING ANOTHER LITHIOAMINE COMPOUND; REDUCING AMOUNT OF SOLVENT NEEDED BRIDGESTONE CORPORATION (JP) 1999-08-10 US disclosed
EP-0894800-A2 Aliphatic solutions of aminoalkyllithium compounds Bridgestone Corporation (JP) 1999-02-03 EP disclosed
US-4335122-A DIURETICS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1982-06-15 US disclosed
US-3993757-A Method of treating inflammation with morphanthridines RICHARDSON-MERRELL INC. (US) 1976-11-23 US disclosed