Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1622048 | 0.97 | SLC6A4 (0.34) | SLC6A3SLC6A4SLC6A2ALDH1A1MAPT | |
| SCHEMBL4691097 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL4931478 | 0.95 | SLC6A3 (0.35) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL27128838 | 0.92 | — | — | |
| SCHEMBL28790729 | 0.77 | — | — | |
| SCHEMBL9114190 | 0.77 | CHRM2 (0.34) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL5605219 | 0.77 | OPRD1 (0.37) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL28205449 | 0.77 | SLC6A3 (0.37) | SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL10499146 | 0.77 | HRH3 (0.42) | SLC6A3SLC6A4SLC6A2ALDH1A1MAPT | |
| SCHEMBL4807714 | 0.76 | FDPS (0.32) | FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237411-A1 | (Piperidino-3)propoxy-5p-cymene, its acetyl, acetoxy and hydroxy derivatives, salts of these products, process for the preparation of these compounds and medicines containing at least one of these products as active principle | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) | 1987-09-16 | — | — | EP | claimed |
| CN-109776551-A | Dioxanes and quinazoline derivant preparation method | 北京工业大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-108467372-A | The preparation method of difenidol hydrochloride | 江苏四环生物制药有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-108467372-A | The preparation method of difenidol hydrochloride | 江苏四环生物制药有限公司 | 2018-08-31 | — | — | CN | disclosed |
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2017-06-29 | — | — | US | disclosed |
| US-9532983-B2 | Benzofuran compounds, compositions, kits and/or methods thereof | SAVANNAH STATE UNIVERSITY (US) | 2017-01-03 | — | — | US | disclosed |
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SAVANNAH STATE UNIVERSITY | 2015-05-14 | — | — | US | disclosed |
| EP-2474533-B1 | PREPARATION OF 1-(SUBSTITUTED BENZYL)-5-TRIFLUOROMETHYL-2-(1H)PYRIDONE COMPOUNDS AND SALTS THEREOF AND THEIR APPLICATIONS | UNIV CENTRAL SOUTH (CN) | 2015-02-25 | — | — | EP | disclosed |
| EP-2436670-B1 | Preparation of 1-(substituted aryl)-5-trifluoromethyl-2-(1H)pyridone compounds and salts thereof and their applications | UNIV CENTRAL SOUTH (CN) | 2014-04-16 | — | — | EP | disclosed |
| CN-102149683-B | 1- (substituted benzyl) -5-trifluoromethyl-2- (1H) pyridone compound and salt thereof, and preparation method and application thereof | UNIV CENTRAL SOUTH | 2013-10-02 | — | — | CN | disclosed |
| US-20010051632-A1 | Phenyl-substituted indolizines and tetrahydroindolizines | ORTHO MCNEIL PHARMACEUTICAL, INC. | 2001-12-13 | — | — | US | disclosed |
| WO-2001074814-A1 | PHENYL-SUBSTITUTED INDOLIZINE DERIVATIVES AND THEIR USE AS HISTAMINE H3 LIGANDS | ORTHO MCNEIL PHARMACEUTICAL, INC. (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-0801649-A2 | HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF | BIOREX KUTATO ES FEJLESZTÖ RT. (HU) | 1997-10-22 | — | — | EP | disclosed |
| WO-1997016439-A1 | HYDROXYLAMINE DERIVATIVES USEFUL FOR ENHANCING THE MOLECULAR CHAPERON PRODUCTION AND THE PREPARATION THEREOF | Biorex Kutató és Fejlesztó Rt. (HU) | 1997-05-09 | — | — | WO | disclosed |
| EP-0237411-A1 | (Piperidino-3)propoxy-5p-cymene, its acetyl, acetoxy and hydroxy derivatives, salts of these products, process for the preparation of these compounds and medicines containing at least one of these products as active principle | INSTITUT DE RECHERCHES CHIMIQUES ET BIOLOGIQUES APPLIQUEES (I.R.C.E.B.A.) Société à responsabilité limitée dite: (FR) | 1987-09-16 | — | — | EP | disclosed |
| EP-0076756-B1 | PYRAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THERAPEUTICAL COMPOSITIONS CONTAINING THEM | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1987-03-04 | — | — | EP | disclosed |
| EP-0037344-B1 | AMINO-ALCOXY PYRAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1984-07-11 | — | — | EP | disclosed |
| EP-0076756-A1 | Pyrazole derivatives, process for their preparation, and therapeutical compositions containing them | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1983-04-13 | — | — | EP | disclosed |
| US-4330544-A | Amino-alkoxy pyrazoles and pharmaceutical compositions | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1982-05-18 | — | — | US | disclosed |
| EP-0037344-A1 | Amino-alcoxy pyrazoles, process for their preparation and medicaments containing them | ETABLISSEMENTS NATIVELLE S.A. (FR) | 1981-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133498-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | SLC6A3 797/4885SLC6A4 430/4885SLC6A2 568/4885 |
| US-20170182023-A1 | BENZOFURAN COMPOUNDS, COMPOSITIONS, KITS AND/OR METHODS THEREOF | SIGMAR1, OPRM1, OPRL1 | SLC6A3 797/4885SLC6A4 430/4885SLC6A2 568/4885 |
| US-20010051632-A1 | Phenyl-substituted indolizines and tetrahydroindolizines | TPH2, TPH1, IDO2 | SLC6A3 64/4885SLC6A4 28/4885SLC6A2 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.