Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 13/20 | 0.55 |
| ▸ | FEN1 | P39748 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31463339 | 1.00 | CA5A (0.59) | CA5AMAPTFEN1ALDH1A1HSD17B10 | |
| SCHEMBL678777 | 0.87 | CA5A (0.53) | CA5AMAPTKDM4EHPGDGAA | |
| SCHEMBL22268360 | 0.85 | CA5A (0.54) | CA5AMAPTALDH1A1HSD17B10GPR3 | |
| SCHEMBL675279 | 0.83 | MAPT (0.50) | CA5AMAPTFEN1 | |
| SCHEMBL675283 | 0.83 | KDM4E (0.50) | CA5AMAPTALDH1A1HSD17B10POLB | |
| SCHEMBL22971581 | 0.82 | MAPT (0.83) | MAPT | |
| SCHEMBL25694432 | 0.81 | MAPT (0.49) | CA5AMAPT | |
| SCHEMBL675828 | 0.78 | IDO1 (0.56) | MAPTALDH1A1POLBCYP1A2CYP3A4 | |
| SCHEMBL19270251 | 0.78 | CA5A (0.47) | CA5AMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL674445 | 0.77 | CA5A (0.53) | CA5AMAPTALDH1A1HSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3375785-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2020-08-05 | — | — | EP | disclosed |
| US-10256420-B2 | Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-04-09 | — | — | US | disclosed |
| US-10256420-B2 | Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2019-04-09 | — | — | US | disclosed |
| US-10193079-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-01-29 | — | — | US | disclosed |
| EP-2976329-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-06-27 | — | — | EP | disclosed |
| US-20170062738-A1 | Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-03-02 | — | — | US | disclosed |
| US-20170062738-A1 | Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2017-03-02 | — | — | US | disclosed |
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | UDC IRELAND LIMITED (IE) | 2016-03-10 | — | — | US | disclosed |
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | UDC IRELAND LIMITED (IE) | 2016-03-10 | — | — | US | disclosed |
| WO-2014146752-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2014-09-25 | — | — | WO | disclosed |
| US-20120061654-A1 | METAL COMPLEX COMPRISING NOVEL LIGAND STRUCTURES | UNIVERSAL DISPLAY CORPORATION (US) | 2012-03-15 | — | — | US | disclosed |
| US-20110281862-A1 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL | UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA (IT) | 2011-11-17 | — | — | US | disclosed |
| WO-2010025872-A2 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL | UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA (IT) | 2010-03-11 | — | — | WO | disclosed |
| EP-2161271-A1 | Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl | Università Degli Studi Di Milano - Bicocca (IT) | 2010-03-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160072076-A1 | MATERIALS FOR ELECTRONIC DEVICES | AOC3, AOC2, AOC1 | CA5A 3465/4885MAPT 3178/4885FEN1 1680/4885 |
| US-20110281862-A1 | ALFA-CARBOLINE INHIBITORS OF NPM-ALK, RET, AND BCR-ABL | ALK, BCR, NPM1 | CA5A 1904/4885MAPT 1494/4885FEN1 4047/4885 |
| US-20170062738-A1 | Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device | PPOX, LAGE3, PDCD1LG2 | CA5A 3485/4885MAPT 2280/4885FEN1 123/4885 |
| US-20120061654-A1 | METAL COMPLEX COMPRISING NOVEL LIGAND STRUCTURES | ZFX, VDAC1, PDCD1LG2 | CA5A 1563/4885MAPT 2467/4885FEN1 1297/4885 |
| US-10256420-B2 | Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device | PPOX, LAGE3, PDCD1LG2 | CA5A 3485/4885MAPT 2280/4885FEN1 123/4885 |
| US-10193079-B2 | Materials for electronic devices | AOC3, AOC2, AOC1 | CA5A 3465/4885MAPT 3178/4885FEN1 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.