Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 5/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15012409 | 0.87 | MEN1 (0.50) | ALDH1A1MEN1KMT2APOLBBCHE | |
| SCHEMBL695671 | 0.84 | MEN1 (0.52) | ALDH1A1MEN1KMT2APOLBBCHE | |
| SCHEMBL9951522 | 0.80 | MEN1 (0.49) | ALDH1A1MEN1KMT2APOLBBCHE | |
| SCHEMBL4695685 | 0.77 | CD274 (0.35) | MEN1KMT2ACD274PDCD1GAA | |
| SCHEMBL1662732 | 0.74 | PDCD1 (0.43) | ALDH1A1MEN1KMT2ACD274PDCD1 | |
| SCHEMBL56141 | 0.74 | P2RX7 (0.43) | MEN1KMT2APOLBBCHEACHE | |
| SCHEMBL13132109 | 0.73 | KMT2A (0.39) | ALDH1A1MEN1KMT2APOLBCD274 | |
| SCHEMBL695065 | 0.72 | MEN1 (0.68) | ALDH1A1MEN1KMT2APOLBBCHE | |
| Hydrochloric Acid SCHEMBL3354807 | 0.72 | MEN1 (0.42) | MEN1KMT2APOLBBCHEACHE | |
| SCHEMBL12138321 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1908763-A1 | Bicyclic compounds | Speedel Experimenta AG (CH) | 2008-04-09 | — | — | EP | disclosed |
| US-20070111989-A1 | Novel diazabicyclononene derivatives and use | ACTELION PHARMACEUTICALS LTD. (CH) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070111989-A1 | Novel diazabicyclononene derivatives and use | REN, ACE, AGTR1 | ALDH1A1 305/4885MEN1 45/4885KMT2A 3009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.