Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.47 |
| ▸ | MMP9 | P14780 | 7/20 | 0.46 |
| ▸ | MMP14 | P50281 | 6/20 | 0.46 |
| ▸ | MMP13 | P45452 | 5/20 | 0.46 |
| ▸ | MMP3 | P08254 | 9/20 | 0.45 |
| ▸ | MMP8 | P22894 | 8/20 | 0.45 |
| ▸ | MMP7 | P09237 | 4/20 | 0.44 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162513 | 1.00 | MMP1 (0.47) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5163119 | 1.00 | MMP1 (0.47) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5160300 | 0.91 | MMP8 (0.49) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5191360 | 0.90 | MMP1 (0.42) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5163191 | 0.90 | MMP1 (0.42) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5160245 | 0.89 | THRB (0.49) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5159963 | 0.89 | THRB (0.49) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5439605 | 0.89 | HTR6 (0.42) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL5431774 | 0.89 | HTR6 (0.42) | MMP1MMP9MMP14MMP13MMP3 | |
| SCHEMBL3311307 | 0.89 | HTR6 (0.42) | MMP1MMP9MMP14MMP13MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763515-B1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-03-12 | — | — | EP | claimed |
| EP-1763515-A1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | Sanofi-Aventis Deutschland GmbH (DE) | 2007-03-21 | — | — | EP | claimed |
| WO-2006002764-A1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-01-12 | — | — | WO | claimed |
| EP-1763515-B1 | 4-TRIFLUOROMETHOXYPHENOXYBENZOL-4'-SULFONIC ACIDS, METHOD FOR THE PRODUCTION AND USE THEREOF IN MEDICAMENTS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-03-12 | — | — | EP | disclosed |