Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | ATP4A | P20648 | 3/20 | 0.36 |
| ▸ | ATP4B | P51164 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.36 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778116 | 0.89 | MAPT (0.39) | PTGDR2POLBRAB9ACYP2C9ALDH1A1 | |
| SCHEMBL6884035 | 0.86 | ATP4A (0.36) | PTGDR2ATP4AATP4BCYP2C9CYP3A4 | |
| SCHEMBL2189523 | 0.78 | ATP4A (0.35) | ATP4AATP4BRAB9ACYP2C9CYP3A4 | |
| SCHEMBL11005326 | 0.77 | ATP1A1 (0.37) | PTGDR2ATP4AATP4BRAB9ACYP2C9 | |
| SCHEMBL11003310 | 0.77 | ATP4A (0.38) | PTGDR2POLBATP4AATP4BRAB9A | |
| SCHEMBL20387989 | 0.75 | POLB (0.38) | PTGDR2POLBRAB9AALDH1A1MAPT | |
| SCHEMBL3185631 | 0.73 | ATP4A (0.32) | ATP4AATP4BRAB9ACYP2C9CYP3A4 | |
| SCHEMBL6871760 | 0.72 | ATP1A1 (0.38) | PTGDR2ATP4AATP4BCYP2C9ALDH1A1 | |
| SCHEMBL5727682 | 0.70 | MEN1 (0.33) | POLBRAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL10817929 | 0.70 | RAB9A (0.40) | POLBRAB9AKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466897-B1 | Process for the preparation of organic compounds containing a sulfinyl or sulfonyl group in the presence of epsilon-phthalimidoperhexanoic acid | DIPHARMA FRANCIS SRL (IT) | 2008-12-17 | — | — | EP | disclosed |
| EP-1963305-A1 | AN IMPROVED PROCESS FOR PREPARING OF, IMPURITIES FREE, SUBSTITUTED 2-BENZIMIDAZOLESULFOXIDE COMPOUND | Pliva Hrvatska D.O.O. (HR) | 2008-09-03 | — | — | EP | disclosed |
| EP-1893602-A2 | PANTOPRAZOLE FREE ACID FORM III | Medichem, S.A. (ES) | 2008-03-05 | — | — | EP | disclosed |
| WO-2007068925-A1 | AN IMPROVED PROCESS FOR PREPARING OF, IMPURITIES FREE, SUBSTITUTED 2-BENZIMIDAZOLESULFOXIDE COMPOUND | PLIVA HRVATSKA D.O.O. (HR) | 2007-06-21 | — | — | WO | disclosed |
| WO-2007036771-A2 | PANTOPRAZOLE FREE ACID FORM III | MEDICHEM, S.A. (US) | 2007-04-05 | — | — | WO | disclosed |
| US-6998490-B2 | Process for the preparation of organic compounds containing a sulfinyl or sulfonyl group | DINAMITE DIPHARMA S.P.A. (IT) | 2006-02-14 | — | — | US | disclosed |
| EP-1615913-A2 | PROCESS FOR PREPARING 2-(PYRIDINYL)METHYL SULFINYL-SUBSTITUTED BENZIMIDAZOLES AND NOVEL CHLORINATED DERIVATIVES OF PANTOPRAZOLE | Teva Pharmaceutical Industries Limited (IL) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004111029-A2 | PROCESS FOR PREPARING 2-[(PYRIDINYL)METHYL]SULFINYL-SUBSTITUTED BENZIMIDAZOLES AND NOVEL CHLORINATED DERIVATIVES OF PANTOPRAZOLE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2004-12-23 | — | — | WO | disclosed |
| EP-1466897-A1 | Process for the preparation of organic compounds containing a sulfinyl or sulfonyl group in the presence of epsilon-phthalimidoperhexanoic acid | Dipharma S.p.A. (IT) | 2004-10-13 | — | — | EP | disclosed |
| US-20040192929-A1 | Process for the preparation of organic compounds containing a sulfinyl or sulfonyl group | DINAMITE DIPHARMA S.P.A. ABBREVIATED DIPHARMA S.P.A. | 2004-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192929-A1 | Process for the preparation of organic compounds containing a sulfinyl or sulfonyl group | STS, MPST, SULT2A1 | PTGDR2 2327/4885POLB 3802/4885ATP4A 4059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.