Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.49 |
| ▸ | ASF1A | Q9Y294 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11489876 | 0.89 | KMT2A (0.52) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11375793 | 0.89 | KMT2A (0.52) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10061888 | 0.78 | ASF1A (0.50) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11804643 | 0.78 | SMN1; SMN2 (0.68) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11804637 | 0.78 | SMN1; SMN2 (0.68) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL974694 | 0.76 | PKM (0.51) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18591033 | 0.76 | ALDH1A1 (0.44) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12793453 | 0.76 | CA1 (0.60) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15382226 | 0.75 | SMN1; SMN2 (0.68) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11804653 | 0.75 | SMN1; SMN2 (0.68) | KMT2AMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614091-B1 | CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER | SHOWA DENKO KK (JP) | 2016-04-20 | — | — | EP | disclosed |
| US-20130059993-A1 | CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX | SHOWA DENKO K.K. (JP) | 2013-03-07 | — | — | US | disclosed |
| US-20130059993-A1 | CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX | SHOWA DENKO K.K. (JP) | 2013-03-07 | — | — | US | disclosed |
| WO-2012033227-A2 | CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER | SHOWA DENKO K.K. (JP) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130059993-A1 | CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX | NNMT, PPOX, DNMT1 | KMT2A 1417/4885MAPT 1168/4885NPC1 3543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.