Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.48 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 4/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469597 | 0.83 | THRA (0.47) | THRAPLA2G2DPDE4APDE4BPDE4C | |
| SCHEMBL10076826 | 0.77 | MAOB (0.43) | — | |
| SCHEMBL456296 | 0.77 | FOLH1 (0.43) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10477860 | 0.76 | KDM4E (0.41) | BCHEACHE | |
| SCHEMBL9574173 | 0.75 | MAOB (0.43) | BCHEACHE | |
| SCHEMBL10592068 | 0.75 | MAOB (0.40) | BCHEACHE | |
| SCHEMBL10488546 | 0.74 | RAF1 (0.38) | BCHEACHEHCRTR2 | |
| SCHEMBL10477760 | 0.74 | MEN1 (0.47) | BCHEACHE | |
| SCHEMBL469521 | 0.73 | PLA2G2D (0.48) | THRAPLA2G2DPDE4BTHRB | |
| SCHEMBL10077369 | 0.73 | CDK1 (0.42) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032546-A2 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |