Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL469526 | 0.83 | THRA (0.48) | THRAPLA2G2DPDE4APDE4BPDE4C | |
| SCHEMBL469521 | 0.73 | PLA2G2D (0.48) | THRAPLA2G2DPDE4BLTB4RPPARG | |
| SCHEMBL469650 | 0.72 | SMN1; SMN2 (0.52) | PLA2G2DMTNR1BMEN1KMT2AMTNR1A | |
| SCHEMBL469539 | 0.71 | PLA2G2D (0.50) | PLA2G2DPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL469709 | 0.70 | ADRB2 (0.73) | MEN1RAB9AKMT2A | |
| SCHEMBL5695106 | 0.69 | SIGMAR1 (0.58) | LTA4HS1PR1S1PR3 | |
| SCHEMBL9417841 | 0.68 | THRA (0.52) | THRAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7772641 | 0.68 | PPARG (0.56) | MEN1KMT2ALTB4RPPARG | |
| SCHEMBL11732623 | 0.68 | PPARG (0.56) | MEN1KMT2ALTB4RPPARG | |
| SCHEMBL10537253 | 0.68 | PPARD (0.61) | MEN1KMT2APPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032546-A2 | PROCESS FOR THE PREPARATION OF SALMETEROL AND ITS INTERMEDIATES | CADILA HEALTHCARE LIMITED (IN) | 2012-03-15 | — | — | WO | disclosed |