Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 15/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895488 | 0.88 | ALDH1A1 (0.44) | ALDH1A1TRPM8GAA | |
| SCHEMBL5440655 | 0.82 | MEN1 (0.41) | ALDH1A1TRPM8GAA | |
| SCHEMBL27638999 | 0.76 | TRPM8 (0.50) | TRPM8GAA | |
| SCHEMBL22615526 | 0.76 | TRPM8 (0.43) | TRPM8NFE2L2GAASLC22A12 | |
| SCHEMBL29688647 | 0.76 | TRPM8 (0.43) | TRPM8NFE2L2GAASLC22A12 | |
| SCHEMBL27656606 | 0.76 | ALDH1A1 (0.56) | ALDH1A1MAPK1GAA | |
| SCHEMBL2009099 | 0.75 | NFE2L2 (0.42) | ALDH1A1MAPK1TRPM8NFE2L2GAA | |
| SCHEMBL29781435 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPK1 | |
| SCHEMBL22553412 | 0.75 | ALDH1A1 (0.55) | ALDH1A1MAPK1 | |
| SCHEMBL4547925 | 0.75 | TRPM8 (0.47) | TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1641800-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| EP-1641800-B1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2008-03-05 | — | — | EP | disclosed |
| US-20070293514-A1 | Triazolopyrimidines | BAYER CROPSCIEMCE AG (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293514-A1 | Triazolopyrimidines | BAYER CROPSCIEMCE AG (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070275985-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-29 | — | — | US | disclosed |
| US-20070275985-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-29 | — | — | US | disclosed |
| US-20070275985-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-11-29 | — | — | US | disclosed |
| US-20070179162-A1 | Triazolopyrimdines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179162-A1 | Triazolopyrimdines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179162-A1 | Triazolopyrimdines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| CN-1809571-A | Fungicidal triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-07-26 | — | — | CN | disclosed |
| CN-1802379-A | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2006-07-12 | — | — | CN | disclosed |
| EP-1644374-A1 | TRIAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| EP-1641798-A1 | TRIAZOLOPYRIMIDINES | Bayer CropScience Aktiengesellschaft (DE) | 2006-04-05 | — | — | EP | disclosed |
| EP-1641800-A1 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-04-05 | — | — | EP | disclosed |
| EP-1638400-A2 | TRIAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005000851-A1 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | WO | disclosed |
| WO-2004112480-A2 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113342-A1 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004108727-A1 | TRIAZOLOPYRIMIDINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293514-A1 | Triazolopyrimidines | QDPR, DPYD, Q6ZSR9 | ALDH1A1 1155/4885MAPK1 3329/4885TRPM8 3567/4885 |
| US-20070179162-A1 | Triazolopyrimdines | QDPR, CYP2D6, CYP1B1 | ALDH1A1 299/4885MAPK1 2242/4885TRPM8 2544/4885 |
| US-20070275985-A1 | Triazolopyrimidines | DPYD, QDPR, P2RX5 | ALDH1A1 395/4885MAPK1 1918/4885TRPM8 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.