Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694086 | 0.89 | TSHR (0.40) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4695322 | 0.88 | TSHR (0.46) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4696911 | 0.86 | TP53 (0.43) | ALDH1A1MAPTSMN1; SMN2LMNACYP3A4 | |
| SCHEMBL4692694 | 0.86 | LMNA (0.46) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4690682 | 0.86 | P2RX7 (0.44) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4694435 | 0.85 | P2RX7 (0.47) | ALDH1A1MAPTSMN1; SMN2RAB9AAVPR2 | |
| SCHEMBL4694270 | 0.85 | HCRTR1 (0.50) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4692889 | 0.85 | MAPT (0.45) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4693334 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2GAALMNA | |
| SCHEMBL4695936 | 0.85 | HCRTR1 (0.47) | ALDH1A1MAPTSMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |