Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.55 |
| ▸ | HTR1D | P28221 | 3/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.50 |
| ▸ | HTR5A | P47898 | 3/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1E | P28566 | 1/20 | 0.50 |
| ▸ | RXFP3 | Q9NSD7 | 3/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700117 | 0.83 | HTR1A (0.53) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| SCHEMBL4701665 | 0.83 | ALDH1A1 (0.49) | HTR6RXFP3MAPTHTTTDP1 | |
| SCHEMBL4701026 | 0.82 | HTR1A (0.48) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| SCHEMBL4699091 | 0.82 | RXFP3 (0.64) | HTR6HTR1DHTR1AHTR5ASLC6A2 | |
| SCHEMBL4231080 | 0.72 | HTR1D (0.74) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| SCHEMBL4244966 | 0.72 | HTR1D (1.00) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| SCHEMBL23602327 | 0.71 | HTR1D (0.63) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| Hydrochloric Acid SCHEMBL7433474 | 0.71 | HTR1D (0.97) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| SCHEMBL7350243 | 0.71 | AKR1C2 (0.64) | HTR6HTR1DMTNR1AMTNR1BHTR1A | |
| SCHEMBL8555235 | 0.71 | HTR1D (0.76) | HTR6HTR1DMTNR1AMTNR1BHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |