Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR6 | P50406 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR5A | P47898 | 2/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4700117 | 0.90 | HTR1A (0.53) | HTR1AHTR6ADRB1ADRB3DRD2 | |
| SCHEMBL4699091 | 0.85 | RXFP3 (0.64) | HTR1AHTR6ADRB1ADRB3DRD2 | |
| SCHEMBL4697190 | 0.82 | HTR6 (0.55) | HTR1AHTR6ADRB1ADRB3DRD2 | |
| SCHEMBL4699037 | 0.78 | ADORA2A (0.51) | HTR1AHTR6HTR2AHTR2CHTR7 | |
| SCHEMBL4700168 | 0.75 | ADORA2A (0.47) | HTR1AHTR6HTR2AHTR2CSLC6A4 | |
| SCHEMBL4701665 | 0.74 | ALDH1A1 (0.49) | HTR6RXFP3SMN1; SMN2 | |
| SCHEMBL4697805 | 0.73 | ADORA2A (0.60) | HTR1AHTR6HTR2AHTR2CHTR7 | |
| SCHEMBL7976809 | 0.69 | MTNR1A (0.58) | MTNR1AMTNR1BMEN1KMT2A | |
| SCHEMBL4700992 | 0.66 | RXFP3 (0.66) | HTR1AHTR6ADRB1ADRB3DRD2 | |
| SCHEMBL4700115 | 0.66 | HTR1A (0.45) | HTR1AHTR2AHTR2BHRH3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | claimed |
| EP-1309544-B1 | COMPOUNDS ACTING AS MELANOCORTIN RECEPTOR LIGANDS | ACURE PHARMA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7153881-B2 | Compounds acting as melanocortin receptor ligands | ACURE PHARMA AB (SE) | 2006-12-26 | — | — | US | disclosed |